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科研机构
上海药物研究所 [32]
内容类型
期刊论文 [32]
发表日期
2020 [32]
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浏览/检索结果:
共32条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents from white ginseng and red ginseng
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 6, 页码: 597-609
作者:
Zuo, Tiantian
;
Zhang, Chunxia
;
Li, Weiwei
;
Wang, Hongda
;
Hu, Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Dimension-enhanced strategy
Multicomponent characterization
Ginsenoside
Offline two-dimensional liquid chromatography
Ion mobility-quadrupole time-of-flight mass spectrometry
In-house database
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Mechanism and optimization of supramolecular complexation-enhanced fluorescence spectroscopy for the determination of SN-38 in plasma and cells
期刊论文
LUMINESCENCE, 2020, 页码: 12
作者:
Zhao, Kena
;
Guo, Tao
;
Sun, Xian
;
Xiong, Ting
;
Ren, Xiaohong
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
cyclodextrins
inclusion complex
pharmacokinetics
SN‐
38
spectrofluorimetric
transfer
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants
期刊论文
ADVANCES IN THERAPY, 2020, 页码: 20
作者:
He, Xin
;
Qiu, Jin-Chun
;
Lu, Ke-Yu
;
Guo, Hong-Li
;
Li, Ling
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
Adenosine receptors
AHR
AOP
Caffeine
Phosphodiesterase
Polymorphism
Therapeutic drug monitoring
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
Bisindole alkaloids with nitric oxide inhibitory activities from an alcohol extract of the Isatis indigotica roots
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 5
作者:
Zhang, Dongdong
;
Sun, Yu
;
Chen, Zhaoqiang
;
Jia, Qi
;
Zhu, Weiliang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Isatis indigotica
Bisindole alkaloids
Nitric oxide production
Isatisindigoticanines J and K
Isatindigosides H-J
Three new indole alkaloid glycosides with unusual structural features from the roots of Isatis indigotica
期刊论文
PHYTOCHEMISTRY LETTERS, 2020, 卷号: 39, 页码: 168-172
作者:
Zhang, Dongdong
;
Sun, Yu
;
Ruan, Deqing
;
Li, Jingyi
;
Chen, Kaixian
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
Isatis indigotica root
Indole alkaloid glycosides
Anti-inflammatory activity
Isatindigosides K and L
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
Chemical structure elucidation of an inulin-type fructan isolated from Lobelia chinensis lour with anti-obesity activity on diet-induced mice
期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 240, 页码: 8
作者:
Zhang, Xue
;
Hu, Pei
;
Zhang, Xiaorui
;
Li, Xiaojun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
Lobelia chinensis Lour polysaccharides
anti-obesity
chemical structure
inulin-type fructan
high fat diet-induced mice
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