QQ客服 官方微博 反馈留言

浏览/检索结果: 共79条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12 作者:  Zheng, Yuan-dong;  Zhang, Hua;  Zhan, Yan;  Bian, Yi-cong;  Ma, Sheng 收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24 vicagrel  [C-14]vicagrel  vicagrel pharmacokinetics  vicagrel metabolism  mass balance  P2Y(12) receptor inhibitor   Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5 作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya 收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24 SMYD2 inhibitors  Thermal shift assay  Structure-activity relationships   Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase 期刊论文 ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003 作者:  Butler, Joshua H.;  Baptista, Rodrigo P.;  Valenciano, Ana L.;  Zhou, Bin;  Kissinger, Jessica C. 收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24 Plasmodium  PfPARE  structure-resistance relationship study  Malaria Box  Pathogen Box  lindenane sesquiterpenoid dimers   Transcriptional and proteomic insights into the host response in fatal COVID-19 cases 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 45, 页码: 28336-28343 作者:  Wu, Meng;  Chen, Yaobing;  Xia, Han;  Wang, Changli;  Tan, Chin Yee 收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  neutrophil  fibrosis  NETosis   The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-beta 1/NDRG2/MAPK Axis 期刊论文 FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 11 作者:  Huang, Hui;  Wang, Kuifeng;  Liu, Qian;  Ji, Feihong;  Zhou, Hu 收藏  |  浏览/下载：32/0  |  提交时间：2020/12/24 HSC  TGF-β  1  liver fibrosis  quantitative proteomics  NDRG2   Teratopyrones A-C, Dimeric Naphtho-gamma-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense 期刊论文 MOLECULES, 2020, 卷号: 25, 期号: 21, 页码: 10 作者:  Xu, Ya-Ming;  Arnold, A. Elizabeth;  U'Ren, Jana M.;  Xuan, Li-Jiang;  Wang, Wen-Qiong 收藏  |  浏览/下载：19/0  |  提交时间：2020/12/24 endophytic fungus  Teratosphaeria  teratopyrones  naphtho-γ  -pyrones  nigerasperone A   Identification of SARS-CoV-2 entry inhibitors among already approved drugs 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Yang, Li;  Pei, Rong-juan;  Li, Heng;  Ma, Xin-na;  Zhou, Yu 收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  virus entry inhibitors  high throughput screening assay  approved drug library  histamine receptor antagonists  clemastine   Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice 期刊论文 TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302 作者:  Zhao, Jie;  Xie, Cen;  Wang, Kanglong;  Takahashi, Shogo;  Krausz, Kristopher W. 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/21 Triptolide  Transcriptomics  Metabolomics  Apoptosis  Acylcarnitine   Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6 作者:  Hu, Wen-juan;  Chang, Lu;  Yang, Ying;  Wang, Xin;  Xie, Yuan-chao 收藏  |  浏览/下载：50/0  |  提交时间：2020/12/21 remdesivir  pharmacokinetics  tissue distribution  nucleotide monophosphate  nucleotide triphosphate  nucleoside   Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983 作者:  Ma, Yuqin;  Luo, Qichao;  Fu, Jie;  Che, Yanxin;  Guo, Fei 收藏  |  浏览/下载：11/0  |  提交时间：2021/05/24