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浏览/检索结果: 共107条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway 期刊论文 SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13 作者:  Xue, Yaru;  Deng, Qiangqiang;  Zhang, Qingli;  Ma, Zhenghua;  Chen, Binfan 收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun 收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   Sesquiterpene lactone dimers from Artemisia lavandulifolia inhibit interleukin-1 beta production in macrophages through activating autophagy 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 105, 页码: 12 作者:  Wang, Qiaoqiao;  Zhang, Tian;  Ke, Chang-Qiang;  Tang, Chunping;  Yao, Sheng 收藏  |  浏览/下载：61/0  |  提交时间：2021/05/24 Artemisia lavandulifolia  Sesquiterpene lactone dimers  IL-1 beta  NLRP3  Autophagy   Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149 作者:  Pan, Lijia;  Nie, Litong;  Yao, Sheng;  Bi, Aiwei;  Ye, Yang 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 neuroblastoma  bufalin  chemical proteomics  ETC  mitochondria   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase 期刊论文 ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003 作者:  Butler, Joshua H.;  Baptista, Rodrigo P.;  Valenciano, Ana L.;  Zhou, Bin;  Kissinger, Jessica C. 收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24 Plasmodium  PfPARE  structure-resistance relationship study  Malaria Box  Pathogen Box  lindenane sesquiterpenoid dimers   Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772 作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo 收藏  |  浏览/下载：75/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352 作者:  Jin, Rui;  Liu, Liang;  Xing, Yun;  Meng, Tao;  Ma, Lanping 收藏  |  浏览/下载：51/0  |  提交时间：2020/12/24 Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408 作者:  Liu, Jian-Guo;  Zhao, Danfeng;  Gong, Qi;  Bao, Fengxia;  Chen, Wen-Wen 收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24 Glycogen synthase kinase-3  bisindole-substituted aminopyrazoles  Alzheimer's disease  oxidative neurotoxicity  microglial inflammation