QQ客服 官方微博 反馈留言

浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2019     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593 作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433 作者:  Guo, Zuhao;  Zhang, Zhuqing;  Yang, Hong;  Cao, Danyan;  Xu, Xiaowei 收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333 作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui 收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 PRMT5 inhibitors  N-Substituted 1,2,3,4-tetrahydroisoquinoline derivatives  Anti-tumor   Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2019, 卷号: 88 作者:  Liu, Renshuai;  Liu, Lulu;  Yang, Xinying;  Fang, Hao 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/11 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid  Apoptosis  Bcl-2  Anti-tumor