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浏览/检索结果: 共32条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15 作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan 收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01 Hippo pathway  TEAD transcription factor  Covalent inhibitor  Palmitoylation inhibitor   Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23 作者:  Zou, Yi;  Hu, Yue;  Ge, Shushan;  Zheng, Yingbo;  Li, Yuezhen 收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01 IDO1  Heme  T cell  Cancer immunotherapy  Virtual screening  Drug design  Molecular dynamics simulation   AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文 PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24 作者:  Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Epigenetics  PRC2  MLL complex  SWI/SNF  DNMT1  allosteric inhibitors   Genetically Encoded Residue-Selective Photo-Crosslinker to Capture Protein-Protein Interactions in Living Cells 期刊论文 CHEM, 2019, 卷号: 5, 期号: 11, 页码: 2955-2968 作者:  Hu, Wei;  Yuan, Yi;  Wang, Cai-Hu;  Tian, Hong-Tao;  Guo, An-Di 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文 ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407 作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing 收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 programmed cell death 1  programmed death-ligand 1  co-culture  immunosuppression  signaling pathway   Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA 期刊论文 CELL DEATH AND DIFFERENTIATION, 2019, 卷号: 26, 期号: 11, 页码: 2329-2343 作者:  Wang, Min;  Mao, Chao;  Ouyang, Lianlian;  Liu, Yating;  Lai, Weiwei 收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01 DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495 作者:  Wan, Fangping;  Zhu, Yue;  Hu, Hailin;  Dai, Antao;  Cai, Xiaoqing 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Deep learning  Machine learning  Drug discovery  In silico drug screening  Compound-protein interaction prediction   Exploring the Ligand Binding/Unbinding Pathway by Selectively Enhanced Sampling of Ligand in a Protein-Ligand Complex 期刊论文 JOURNAL OF PHYSICAL CHEMISTRY B, 2019, 卷号: 123, 期号: 38, 页码: 7974-7983 作者:  Shao, Qiang;  Zhu, Weiliang 收藏  |  浏览/下载：2/0  |  提交时间：2020/07/01 Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1 期刊论文 ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007 作者:  Trevarton, Alexander J.;  Zhou, Yan;  Yang, Dehua;  Rewcastle, Gordon W.;  Flanagan, Jack U. 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 Cancer  YB-1  Luciferase  AlphaScreen  Transcription factor  Single-stranded DNA