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CORC

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High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 6, 页码: 889-899
作者:  Yuliantie, Elita;  Dai, Xinchuan;  Yang, Dehua;  Crack, Peter J.;  Wang, Ming-Wei
收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/10
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang
收藏  |  浏览/下载：32/0  |  提交时间：2019/08/23
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
Anti-estrogenic activity of tris(2,3-dibromopropyl) isocyanurate through disruption of co-activator recruitment: experimental and computational studies 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 4, 页码: 1471-1482
作者:  Cao, Huiming;  Li, Xun;  Zhang, Wenjuan;  Wang, Ling;  Pan, Yu
收藏  |  浏览/下载：28/0  |  提交时间：2019/06/20
Anti-estrogenic activity of tris(2,3-dibromopropyl) isocyanurate through disruption of co-activator recruitment: experimental and computational studies 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 4, 页码: 1471-1482
作者:  Liang, Yong;  Cao, Huiming;  Li, Xun;  Zhang, Wenjuan;  Wang, Ling
收藏  |  浏览/下载：33/0  |  提交时间：2018/12/29
Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762
作者:  Ai, Jing;  Chen, Yi;  Peng, Xia;  Ji, Yinchun;  Xi, Yong
收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08

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