×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [5]
山东大学 [3]
中国医学科学院 北京... [2]
西安交通大学 [1]
自动化研究所 [1]
吉林大学白求恩第一医... [1]
更多...
内容类型
期刊论文 [14]
发表日期
2018 [14]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共14条,第1-10条
帮助
限定条件
发表日期:2018
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Optimization of Red Luminescent Intensity in Eu3+-Doped Lanthanide Phosphors Using Genetic Algorithm
期刊论文
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 卷号: 4, 期号: 12, 页码: 4378-4384
作者:
Lv, Ruichan
;
Xiao, Liyang
;
Jiang, Xue
;
Feng, Miao
;
Yang, Fan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/07/12
Eu3+-doped phosphors
optimization algorithm
genetic algorithm
bioimaging
fingerprint detection
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:
Hao, Yongjia
;
Lyu, Jiankun
;
Qu, Rong
;
Tong, Yi
;
Sun, Deheng
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
收藏
  |  
浏览/下载:177/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306
作者:
Yan, Qi
;
Chen, Yuzhe
;
Tang, Baiyou
;
Xiao, Qiang
;
Qu, Rong
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
EGFR inhibitors
Pyrimidine derivatives
Mutant selective inhibitors
AZD9291
T790M
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo
期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:
Zhang, Zhang
;
Zou, Jian
;
Yu, Lei
;
Luo, Jinfeng
;
Li, Yan
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/01/08
EGFR inhibitor
lung cancer
pharmacokinetic
selectively
T790M mutation
Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397
作者:
Geng, Kaijun
;
Xia, Zongjun
;
Ji, Yinchun
;
Zhang, Ruisi (Ruthy)
;
Sun, Deqiao
收藏
  |  
浏览/下载:155/0
  |  
提交时间:2019/01/08
ALK
G1202R mutant
Drug resistance
2,4-Diarylaminopyrimidine
Resorcinol
A Novel GJB2 compound heterozygous mutation c.257C > G (p.T86R)/c.176del16 (p.G59A fs*18) causes sensorineural hearing loss in a Chinese family
期刊论文
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2018, 卷号: 32, 期号: 7
作者:
Shi, Xi
;
Zhang, Yan
;
Qiu, Shiwei
;
Zhuang, Wei
;
Yuan, Na
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
compound heterozygous mutation
GJB2
molecular dynamics simulation
sequence analysis
SNHL
Whole-exome sequencing identifies rare compound heterozygous mutations in the MYBPC3 gene associated with severe familial hypertrophic cardiomyopathy
期刊论文
EUROPEAN JOURNAL OF MEDICAL GENETICS, 2018, 卷号: 61, 期号: 8
作者:
Zhou, Nianwei
;
Qin, Shengmei
;
Li, Yili
;
Tang, Lu
;
Zha, Weipeng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Gene sequencing
Hypertrophic cardiomyopathy
MYBPC3
Mutation
A hERG mutation E1039X produced a synergistic lesion on &ITI&ITKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Wu, Jie
;
Mizusawa, Yuka
;
Ohno, Seiko
;
Ding, Wei-Guang
;
Higaki, Takashi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Basal ganglia calcification and novel compound heterozygous mutations in the PANK2 gene in a Chinese boy with classic Pantothenate kinase-associated neurodegeneration A case report
期刊论文
MEDICINE, 2018, 卷号: 97, 期号: 15
作者:
Shi, Xulai
;
Zheng, Feixia
;
Ye, Xiuyun
;
Li, Xiucui
;
Zhao, Qianlei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
calcification
heterozygous mutation
PANK2 gene mutation
pantothenate
kinase-associated neurodegeneration
©版权所有 ©2017 CSpace - Powered by
CSpace