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Optimization of Red Luminescent Intensity in Eu3+-Doped Lanthanide Phosphors Using Genetic Algorithm 期刊论文
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 卷号: 4, 期号: 12, 页码: 4378-4384
作者:  Lv, Ruichan;  Xiao, Liyang;  Jiang, Xue;  Feng, Miao;  Yang, Fan
收藏  |  浏览/下载:43/0  |  提交时间:2019/07/12
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Tong, Yi;  Sun, Deheng
收藏  |  浏览/下载:62/0  |  提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin
收藏  |  浏览/下载:177/0  |  提交时间:2019/01/08
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载:79/0  |  提交时间:2019/01/08
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan
收藏  |  浏览/下载:71/0  |  提交时间:2019/01/08
Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397
作者:  Geng, Kaijun;  Xia, Zongjun;  Ji, Yinchun;  Zhang, Ruisi (Ruthy);  Sun, Deqiao
收藏  |  浏览/下载:155/0  |  提交时间:2019/01/08
A Novel GJB2 compound heterozygous mutation c.257C > G (p.T86R)/c.176del16 (p.G59A fs*18) causes sensorineural hearing loss in a Chinese family 期刊论文
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2018, 卷号: 32, 期号: 7
作者:  Shi, Xi;  Zhang, Yan;  Qiu, Shiwei;  Zhuang, Wei;  Yuan, Na
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/05
Whole-exome sequencing identifies rare compound heterozygous mutations in the MYBPC3 gene associated with severe familial hypertrophic cardiomyopathy 期刊论文
EUROPEAN JOURNAL OF MEDICAL GENETICS, 2018, 卷号: 61, 期号: 8
作者:  Zhou, Nianwei;  Qin, Shengmei;  Li, Yili;  Tang, Lu;  Zha, Weipeng
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
A hERG mutation E1039X produced a synergistic lesion on &ITI&ITKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Wu, Jie;  Mizusawa, Yuka;  Ohno, Seiko;  Ding, Wei-Guang;  Higaki, Takashi
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/26
Basal ganglia calcification and novel compound heterozygous mutations in the PANK2 gene in a Chinese boy with classic Pantothenate kinase-associated neurodegeneration A case report 期刊论文
MEDICINE, 2018, 卷号: 97, 期号: 15
作者:  Shi, Xulai;  Zheng, Feixia;  Ye, Xiuyun;  Li, Xiucui;  Zhao, Qianlei
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/11


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