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High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells. 期刊论文
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2018
作者:  Li, Yanjiao;  Raj, J. Usha;  Qu, Junle;  Luo, Yixuan;  Chen, Jidong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/31
Photothermal therapy with AuNRs and EGFRmAb-AuNRs inhibits subcutaneous transplantable hypopharyngeal tumors in nude mice 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 6
作者:  Zhang, Yingying;  He, Jiayan;  Wang, Yu;  Wen, Jinya;  Zou, Yingying
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/04
Silence of alpha 1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells 期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24
作者:  Zhao, Zhijing;  Ma, Junfeng;  Mao, Ying;  Dong, Liying;  Li, Siqi
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/04
Genetic diversity of the Plasmodium vivax phosphatidylinositol 3-kinase gene in two regions of the China-Myanmar border 期刊论文
INFECTION GENETICS AND EVOLUTION, 2018, 卷号: 61
作者:  Mbenda, Huguette Gaelle Ngassa;  Zeng, Weilin;  Bai, Yao;  Siddiqui, Faiza Amber;  Yang, Zhaoqing
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/04
2-Methoxyestradiol inhibits hypoxia-induced scleroderma fibroblast collagen synthesis by phosphatidylinositol 3-kinase/Akt/mTOR signalling 期刊论文
RHEUMATOLOGY, 2018, 卷号: 57, 期号: 9
作者:  Zhou, Xing;  Liu, Chaofan;  Lu, Jinghao;  Zhu, Lubing;  Li, Ming
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05


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