Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells. | |
Li, Yanjiao; Raj, J. Usha; Qu, Junle; Luo, Yixuan; Chen, Jidong; Lin, Boya; Qian, Zhengjiang; Li, Li; Gou, Deming | |
刊名 | JOURNAL OF THE AMERICAN HEART ASSOCIATION |
2018 | |
文献子类 | 期刊论文 |
英文摘要 | Background-Platelet-derived growth factor BB, a potent mitogen of pulmonary artery smooth muscle cells (PASMCs), has been implicated in pulmonaryarterial remodeling, which is a key pathogenic feature of pulmonary arterial hypertension. Previous microRNA profiling in platelet-derived growth factor BB-treated PASMCs found a significantly downregulated microRNA, miR-1281, but it has not been associated with any cellular function, and we investigated the possibility. |
URL标识 | 查看原文 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/13861] |
专题 | 深圳先进技术研究院_脑所 |
推荐引用方式 GB/T 7714 | Li, Yanjiao,Raj, J. Usha,Qu, Junle,et al. Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells.[J]. JOURNAL OF THE AMERICAN HEART ASSOCIATION,2018. |
APA | Li, Yanjiao.,Raj, J. Usha.,Qu, Junle.,Luo, Yixuan.,Chen, Jidong.,...&Gou, Deming.(2018).Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells..JOURNAL OF THE AMERICAN HEART ASSOCIATION. |
MLA | Li, Yanjiao,et al."Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells.".JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018). |
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