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Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy 期刊论文
Biochemical pharmacology, 2018, 卷号: 159, 页码: 82-95
作者:  Mei, Xiyu;  Zhang, Tianyu;  Ouyang, Hao;  Lu, Bin;  Wang, Zhengtao
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway 期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: 45, 期号: 6
作者:  Peng, Sheng;  Yan, Hong-Zhu;  Liu, Pei-Rong;  Shi, Xiao-Wei;  Liu, Chun-Liang
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 502, 期号: 1, 页码: 110-115
作者:  Shen, Xing;  Xing, Shuang;  Zhang, Lu;  Wang, Fangmin;  Ou, Hongling
收藏  |  浏览/下载:58/0  |  提交时间:2019/03/29
Efficacy of the MEK Inhibitor Cobimetinib and its Potential Application to Colorectal Cancer Cells. 期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: Vol.47 No.2, 页码: 680-693
作者:  Gong, S;  Xu, DS;  Zhu, JL;  Zou, FD;  Peng, R
收藏  |  浏览/下载:1/0  |  提交时间:2019/02/25
Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway 期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: 45, 页码: 2329-2337
作者:  Peng Sheng[1];  Yan Hong-Zhu[2];  Liu Pei-Rong[3];  Shi Xiao-Wei[4];  Liu Chun-Liang[5]
收藏  |  浏览/下载:7/0  |  提交时间:2019/04/24
ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells 期刊论文
Journal of Experimental & Clinical Cancer Research, 2018, 卷号: Vol.37 No.1, 页码: 1-14
作者:  Sheng Zhou;  Hongwei Xia;  Huanji Xu;  Qiulin Tang;  Yongzhan Nie
收藏  |  浏览/下载:4/0  |  提交时间:2019/02/25
ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells 期刊论文
Journal of Experimental & Clinical Cancer Research, 2018, 卷号: Vol.37 No.1, 页码: 1-14
作者:  Sheng Zhou;  Hongwei Xia;  Huanji Xu;  Qiulin Tang;  Yongzhan Nie
收藏  |  浏览/下载:8/0  |  提交时间:2019/02/25
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2018, 卷号: 142, 期号: 2, 页码: 381-391
作者:  de Gooijer, Mark C.;  Zhang, Ping;  Weijer, Ruud;  Buil, Levi C. M.;  Beijnen, Jos H.
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11


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