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Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104
作者:  Wang, Yuming;  Li, Lijun;  Fan, Jun;  Dai, Yang;  Jiang, Alan
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Tong, Yi;  Sun, Deheng
收藏  |  浏览/下载:61/0  |  提交时间:2019/01/08
Quinone skeleton as a new class of irreversible inhibitors against Staphylococcus aureus sortase A 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 10, 页码: 1864-1869
作者:  Hou, Xiaochen;  Wang, Meining;  Wen, Yi;  Ni, Tengfeng;  Guan, Xiangna
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang
收藏  |  浏览/下载:32/0  |  提交时间:2019/08/23
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Molecular Modeling Studies on Carbazole Carboxamide Based BTK Inhibitors Using Docking and Structure-Based 3D-QSAR 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4
作者:  Li, Rui;  Du, Yongli;  Gao, Zhipei;  Shen, Jingkang
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Discovery and biological evaluation of N5-substituted 6,7-dioxo-6,7-dihydropteridine derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 4, 页码: 697-704
作者:  Chen, Haiyang;  Song, Peiran;  Diao, Yanyan;  Hao, Yongjia;  Dou, Dou
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan
收藏  |  浏览/下载:70/0  |  提交时间:2019/01/08
Allenamide as a bioisostere of acrylamide in the design and synthesis of targeted covalent inhibitors 期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 2, 页码: 244-253
作者:  Chen, Deheng;  Guo, Dexiang;  Yan, Ziqin;  Zhao, Yujun
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08


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