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科研机构
上海药物研究所 [5]
复旦大学上海医学院 [3]
昆明植物研究所 [1]
山东大学 [1]
吉林大学白求恩第三医... [1]
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期刊论文 [11]
发表日期
2018 [11]
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The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
Discovery of FS36 as a Novel Human Hsp90 Inhibitor
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 7, 页码: 736-744
作者:
Li Gen
;
Lu Kai-Kai
;
Li Jian
;
Yin Xiu-Shan
;
Zhao Dong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
heat shock protein 90
antitumor drugs
inhibitor
X-ray diffraction
complex crystal structure
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
收藏
  |  
浏览/下载:177/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
Vibsane-Type Diterpenoids from Viburnum odoratissimum and Their Cytotoxic and HSP90 Inhibitory Activities
期刊论文
CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 5, 页码: 1800049
作者:
Zhu, Qin-Feng
;
Qi, Yan-Yan
;
Zhang, Zhi-Jun
;
Fan, Min
;
Bi, Ran
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2018/07/16
Vibsane-type Diterpenoids
Viburnum Odoratissimum
Cytotoxicity
Hsp90 Inhibitor
Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis
期刊论文
ONCOTARGETS AND THERAPY, 2018, 卷号: 11
作者:
Sun, Libo
;
Yang, Shoujun
;
Chi, Guonan
;
Jin, Xingyi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
NMS-E973
PUMA
glioblastoma
apoptosis
In vitro interactions between 17-AAG and azoles against Exophiala dermatitidis
期刊论文
MYCOSES, 2018, 卷号: 61, 期号: 11
作者:
Gao, Lujuan
;
Sun, Yi
;
He, Chengyan
;
Li, Ming
;
Zeng, Tongxiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
17-AAG
azole
Exophiala dermatitidis
Hsp90 inhibitor
synergy
Simvastatin functions as a heat shock protein 90 inhibitor against triple-negative breast cancer
期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 10
作者:
Kou, Xinhui
;
Jiang, Xiaoxiao
;
Liu, Huijuan
;
Wang, Xuan
;
Sun, Fanghui
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
acetylation
Cdc37
Hsp90
LBH589
simvastatin
Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2018, 卷号: 14, 期号: 3
作者:
Lam, Kit S.
;
Long, Qilai
;
Lin, Tzu-yin
;
Huang, Yee
;
Li, Xiaocen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Photodynamic therapy
Photothermal therapy
HSP90 inhibitor
Bladder cancer
Nanoparticle
Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 551-558
作者:
Wei, Qun
;
Ning, Jun-Ya
;
Dai, Xi
;
Gao, Yuan-Di
;
Su, Le
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Coumarin
Pyrazoline
HSP90 inhibitor
Lung cancer cell
Apoptosis
Autophagy
DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp9O-Cdc37 interaction
期刊论文
CANCER LETTERS, 2018, 卷号: 434, 页码: 70-80
作者:
Chen, Xiangling
;
Liu, Peng
;
Wang, Quanren
;
Li, Yun
;
Fu, Li
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Cdc37
DCZ3112
Geldanamycin
Hsp90
HER2-positive breast cancer
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