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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway 期刊论文 ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 6, 页码: 889-899 作者:  Yuliantie, Elita;  Dai, Xinchuan;  Yang, Dehua;  Crack, Peter J.;  Wang, Ming-Wei 收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 High-throughput screening  Interferon alpha receptor  Secreted embryonic alka-line phosphatase  JAK-STAT  IFN regulatory factor  Inhibitor   Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 Proliferation  Anticancer drug  Phosphatidylinositol 3-kinase inhibitor  Apoptosis  Structure-activity relationship   Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562 作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Mitogen-activated protein kinases  Extracellular signal-regulated kinase  ERK inhibitor  ERK kinase  Cancer therapy  Drug resistance   Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627 作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文 Acta pharmacologica Sinica, 2018 作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762 作者:  Ai, Jing;  Chen, Yi;  Peng, Xia;  Ji, Yinchun;  Xi, Yong 收藏  |  浏览/下载：52/0  |  提交时间：2019/01/08 A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma 期刊论文 THERANOSTICS, 2018, 卷号: 8, 期号: 12, 页码: 3256-3267 作者:  Sun, Jingya;  Wang, Xin;  Tang, Boyun;  Liu, Hongchun;  Zhang, Minmin 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 dasatinib  YAP  Src  renal cell carcinoma   The dual-inhibitory effect of miR-338-5p on the multidrug resistance and cell growth of hepatocellular carcinoma 期刊论文 Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 3 作者:  Zhao, Yang;  Chen, Jing;  Wei, Wenxin;  Qi, Xinming;  Li, Chunzhu 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 targetingerkanachillesheelofthemapkpathwayincancertherapy 期刊论文 actapharmaceuticasinicab, 2018, 卷号: 8, 期号: 4, 页码: 552 作者:  Liu Feifei;  Yang Xiaotong;  Geng Meiyu;  Huang Min 收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01 Mitogen-activated protein kinases  Extracellular signal-regu lated kinase  ERK inhibitor  ERK kinase  Cancer therapy  Drug resistance   highthroughputscreeningforsmallmoleculeinhibitorsofthetypeiinterferonsignalingpathway 期刊论文 actapharmaceuticasinicab, 2018, 卷号: 000, 期号: 006, 页码: 889 作者:  Yuliantie Elita;  Dai Xinchuan;  Yang Dehua;  Crack Peter J;  Wang Mingwei 收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01 High-throughput  screening  Interferon  α  receptor  Secreted  embryonic  alkaline  phosphatase  JAK-STAT  IFN  regulatory  factor  Inhibitor