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上海药物研究所 [12]
西北高原生物研究所 [9]
武汉植物园 [3]
大连化学物理研究所 [2]
昆明植物研究所 [2]
南海海洋研究所 [1]
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期刊论文 [36]
发表日期
2017 [36]
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Pharmacolo... [1]
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Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
Cross-Dehydrogenative Coupling Reactions Applied in the Construction of Privileged Heterocycles
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 11, 页码: 2850-2858
作者:
Hu, Wei
;
Long, Yaqiu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
cross-dehydrogenative coupling
C-H functionalization
drug-like privileged scaffold
Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity
期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
作者:
Niu, Yanfen
;
Li, Hongjian
;
Gao, Lihui
;
Lin, Hua
;
Kung, Hsiangfu
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2018/05/08
Olsalazine Sodium
Hyperuricemia
Xanthine Oxidase
Uric Acid
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195
作者:
Hu, Jianping
;
Wang, Yingqing
;
Li, Yanlian
;
Xu, Lin
;
Cao, Danyan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
BRD4 inhibitor
Kinase
BI-2536
Dihydroquinoxalin-2(1H)-one
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Paecilomyces tenuipes extract prevents depression-like behaviors in chronic unpredictable mild stress-induced rat model via modulation of neurotransmitters
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 期号: 2, 页码: 2172-2178
作者:
Liu, Yang
;
Lee, Robert J.
;
Wang, Juan
;
Wang, Di
;
Liu, Chungang
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  |  
浏览/下载:35/0
  |  
提交时间:2017/10/29
Paecilomyces tenuipes
chronic unpredictable mild stress
antidepression
neurotransmitters
Comparative Analysis of Saponins from Different Phytolaccaceae Species and Their Antiproliferative Activities
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 7, 页码: 17
作者:
Li, Xun
;
Saleri, Flora Didii
;
Chen, Guilin
;
Guo, Mingquan
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  |  
浏览/下载:26/0
  |  
提交时间:2017/12/31
Phytolacca acinosa
Phytolacca americana
triterpenoid saponin
ultrasound-assisted extraction
LC-MS
antiproliferative activities
Design and optimization of purine derivatives as in vivo active PDE10A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 13, 页码: 3315-3329
作者:
Chen, Liu
;
Chen, Danqi
;
Tang, Le
;
Ren, Jing
;
Chen, Jiaojiao
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Phosphodiesterase
PDE10A
Purine
Inhibitor
Anti-psychotic
Structure-activity relationships of the antimalarial agent artemisinin and the research progress on the artemisinin analogues with novel pharmacological actions
期刊论文
Kexue Tongbao/Chinese Science Bulletin, 2017, 卷号: 62, 期号: 18, 页码: 1948-1963
作者:
Zheng, Mingyue
;
Liu, Gang
;
Tang, Wei
;
Zuo, Jianping
;
Zhang, Ao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 17, 页码: 7095-7104
作者:
Li, Zhong
;
Du, Lei
;
Zhang, Wei
;
Zhang, Xingwang
;
Jiang, Yuanyuan
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2017/12/14
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