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CORC

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Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047
作者:  Yang, Zhong-min;  Liao, Xue-mei;  Chen, Yi;  Shen, Yan-yan;  Yang, Xin-ying
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
Discovery of cancer common and specific driver gene sets 期刊论文
NUCLEIC ACIDS RESEARCH, 2017, 卷号: 45, 期号: 10, 页码: 14
作者:  Zhang, Junhua;  Zhang, Shihua
收藏  |  浏览/下载：20/0  |  提交时间：2018/07/30
过渡金属催化的烯胺膦氧化反应及一种新型PARP-1抑制剂的研究 学位论文
: 中国科学院大学, 2017
作者:  梁伍
收藏  |  浏览/下载：48/0  |  提交时间：2018/08/28
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells 期刊论文
JOURNAL OF CELL BIOLOGY, 2017, 卷号: 216, 期号: 2, 页码: 409-424
作者:  Qu, Jia;  Sun, Wenyi;  Zhong, Jie;  Lv, Hao;  Zhu, Mingrui
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
OlympiAD: Phase III trial of olaparib monotherapy versus chemotherapy for patients (pts) with HER2-negative metastatic breast cancer (mBC) and a germline BRCA mutation (gBRCAm) 期刊论文
Journal of Clinical Oncology, 2017, 卷号: 35
作者:  Robson M.E., Im S.-A., Senkus E., Xu B., Domchek S.M., Masuda N., Delaloge S., Li W., Tung N.M., Armstrong A., Wu W., Goessl C.D., Runswick S., Conte P.F.
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
OlympiAD: Phase III trial of olaparib monotherapy versus chemotherapy for patients (pts) with HER2-negative metastatic breast cancer (mBC) and a germline BRCA mutation (gBRCAm). 会议论文
作者:  Robson, Mark E.;  Im, Seock-Ah;  Senkus, Elzbieta;  Xu, Binghe;  Domchek, Susan M.
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05
OlympiAD: Further efficacy outcomes in patients with HER2-negative metastatic breast cancer and a germline BRCA mutation receiving olaparib monotherapy vs standard single-agent chemotherapy treatment of physician"s choice 会议论文
作者:  Runswick, S.;  Robson, M.;  Conte, P. F.;  Im, S-A.;  Senkus-Konefka, E.
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05

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