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复旦大学上海医学院 [25]
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期刊论文 [100]
会议论文 [9]
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2017 [112]
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Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Zhu, Weiliang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Biomimetic Magnetosomes as Versatile Artificial Antigen-Presenting Cells to Potentiate T-Cell-Based Anticancer Therapy
期刊论文
ACS NANO, 2017, 卷号: 11, 期号: 11, 页码: 10724-10732
作者:
Zhang, Qanmei
;
Wei, Wei
;
Wang, Peilin
;
Zuo, Liping
;
Li, Feng
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浏览/下载:36/0
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提交时间:2018/01/19
Biomimetic
Artificial Antigen-presenting Cells
Targeting Delivery
T-cell Therapy
DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway
期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8
作者:
Sun, Xi
;
Li, Bo
;
Xie, Bingqian
;
Xu, Zhijian
;
Chang, Gaomei
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  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557
作者:
Wang, Beilei
;
Deng, Yuanxin
;
Chen, Yongfei
;
Yu, Kailin
;
Wang, Aoli
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  |  
浏览/下载:39/0
  |  
提交时间:2018/08/16
Btk
Kinase Inhibitor
Irreversible Inhibitor
Structure-activity Relationship
B-cell Lymphoma
Dietary protein levels regulated antibacterial activity, inflammatory response and structural integrity in the head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) after challenged with Aeromonas hydrophila
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 68, 期号: 1, 页码: 154-172
作者:
Jiang, Wei-Dan
;
Xu, Jing
;
Zhou, Xiao-Qiu
;
Wu, Pei
;
Liu, Yang
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  |  
浏览/下载:21/0
  |  
提交时间:2019/09/26
Protein
Grass carp (Ctenopharyngodon idella)
Disease resistance
Immune function
Structural integrity
Dietary myo-inositol deficiency decreased the growth performances and impaired intestinal physical barrier function partly relating to nrf2, jnk, e2f4 and mlck signaling in young grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 67, 期号: 1, 页码: 475-492
作者:
Li, Shuang-An
;
Jiang, Wei-Dan
;
Feng, Lin
;
Liu, Yang
;
Wu, Pei
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  |  
浏览/下载:21/0
  |  
提交时间:2019/08/01
Myo-inositol
Grass carp (Ctenopharyngodon idella)
Intestine
Antioxidant
Apoptosis
Proliferation
Tight junction
Decreased enteritis resistance ability by dietary low or excess levels of lipids through impairing the intestinal physical and immune barriers function of young grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 67, 期号: 1, 页码: 493-512
作者:
Feng, Lin
;
Ni, Pei-Jun
;
Jiang, Wei-Dan
;
Wu, Pei
;
Liu, Yang
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  |  
浏览/下载:17/0
  |  
提交时间:2019/08/01
Ctenopharyngodon idella
Lipids
Intestine
Bacterial challenge
Physical barrier
Immune barrier
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6289-6304
作者:
Mao, Ruifeng
;
Shao, Jingwei
;
Zhu, Kongkai
;
Zhang, Yuanyuan
;
Ding, Hong
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  |  
浏览/下载:91/0
  |  
提交时间:2019/01/08
Model-free feature screening for ultrahigh dimensional censored regression
期刊论文
STATISTICS AND COMPUTING, 2017, 卷号: 27, 期号: 4, 页码: 947-961
作者:
Zhou, Tingyou
;
Zhu, Liping
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浏览/下载:5/0
  |  
提交时间:2019/08/22
Censored data
Feature screening
Ranking consistency
Sure screening property
Ultrahigh dimensional data
The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-kappa B, p38MAPK, Nrf2 and MLCI(signaling in head kidney, spleen and skin of grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 65, 期号: 1, 页码: 145-168
作者:
Guo, Yan-Lin
;
Jiang, Wei-Dan
;
Wu, Pei
;
Liu, Yang
;
Zhou, Xiao-Qiu
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  |  
浏览/下载:18/0
  |  
提交时间:2019/09/02
Iron deficiency
Grass carp (Ctenopharyngodon idella)
Immune function
Structural integrity
Head kidney
Spleen
Sldn
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