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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Versatile Tailoring of NH2-Containing Metal-Organic Frameworks with Paddle-Wheel Units 期刊论文 CHEMISTRY-A EUROPEAN JOURNAL, 2017, 卷号: 23, 期号: 70, 页码: 17727-17733 作者:  Guo, Xiang-Guang;  Zhang, Zai-Yong;  Qiu, Sen;  Su, Xiang;  Wang, Ya-Bing 收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 amines  luminescence  metal-organic frameworks  pillar structures  X-ray diffraction   Detection of Membrane Protein Interactions by Cell-based Tango Assays 期刊论文 Bio-protocol, 2017, 卷号: 7, 期号: 22 作者:  Yan, Yan;  Xu, Ting-Hai;  Harikumar, Kaleeckal G;  Miller, Laurence J;  Melcher, Karsten 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control 期刊论文 SCIENTIFIC REPORTS, 2017, 卷号: 7 作者:  Tang, Yubo;  Tang, Feng;  Yang, Yang;  Zhao, Lei;  Zhou, Hu 收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08 Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells 期刊论文 CANCER SCIENCE, 2017, 卷号: 108, 期号: 7, 页码: 1458-1468 作者:  Wang, Hongbin;  Wang, Wenqian;  Xu, Yongping;  Yang, Yong;  Chen, Xiaoyan 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Antibody-drug conjugate  drug resistance  HER2  T-DM1  V-ATPase   Discovery of Novel Pyridone-Conjugated Monosulfactams as Potent and Broad-Spectrum Antibiotics for Multidrug-Resistant Gram-Negative Infections 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2669-2684 作者:  Tan, Liang;  Tao, Yunliang;  Wang, Ting;  Zou, Feng;  Zhang, Shuhua 收藏  |  浏览/下载：52/0  |  提交时间：2019/01/08 Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature 期刊论文 BIOMATERIALS, 2017, 卷号: 116, 页码: 57-68 作者:  Chen, Yingzhi;  Zhang, Meng;  Jin, Hongyue;  Tang, Yisi;  Wang, Huiyuan 收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Intein-mediated protein ligation (IPL)  Protein toxin  Trichosanthin  Site-specific PEGylation  Gelatinase  Cell-penetrating peptide   Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 315-326 作者:  Zhang, Chi;  Wang, Xin;  Liu, Hongchun;  Zhang, Minmin;  Geng, Meiyu 收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 Diarylisoxazole  Resorcinol  Amino acid  Hsp90 inhibitor  Antiproliferative effect   Ordered and disordered cyclodextrin nanosponges with diverse physicochemical properties 期刊论文 RSC ADVANCES, 2017, 卷号: 7, 期号: 38, 页码: 23759-23764 作者:  Singh, Vikramjeet;  Xu, Jianghui;  Wu, Li;  Liu, Botao;  Guo, Tao 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08