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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2017    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition 期刊论文 EBIOMEDICINE, 2017 Wang, Li-Chao; Liao, Li-Xi; Lv, Hai-Ning; Liu, Dan; Dong, Wei; Zhu, Jian; Chen, Jin-Feng; Shi, Meng-Ling; Fu, Ge; Song, Xiao-Min; Jiang, Yong; Zeng, Ke-Wu; Tu, Peng-Fei 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 Heat shock protein 70 (Hsp70)  Handelin  Drug target  Covalent modification  Neuroinflammation  HEAT-SHOCK PROTEINS  T-CELL REGULATION  HIGH-FAT DIET  KAPPA-B  AUTOIMMUNE ARTHRITIS  HSP70  STRESS  INFLAMMATION  EXPRESSION  POLYUBIQUITINATION   Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection 期刊论文 IMMUNITY, 2017 Wang, Yutao; Ning, Xiaohan; Gao, Pengfei; Wu, Shuxian; Sha, Mengyin; Lv, Mengze; Zhou, Xiang; Gao, Juyi; Fang, Run; Meng, Guangxun; Su, Xiaodong; Jiang, Zhengfan 收藏  |  浏览/下载：108/0  |  提交时间：2017/12/03 NF-KAPPA-B  CYCLIC GMP-AMP  PYROPTOTIC CELL-DEATH  DOUBLE-STRANDED-RNA  I INTERFERON  RIG-I  CYTOSOLIC DNA  ADAPTER PROTEIN  HOST-DEFENSE  INNATE   Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response 期刊论文 JOURNAL OF VIROLOGY, 2017 Zhang, Rui; Xu, Aotian; Qin, Chao; Zhang, Qiong; Chen, Shifan; Lang, Yue; Wang, Mengdong; Li, Chuang; Feng, Wenhai; Zhang, Rui; Jiang, Zhengfan; Tang, Jun 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 alphaherpesviruses  interferon signaling  type I interferon receptor 1  dUTPase UL50  pseudorabies virus  NF-KAPPA-B  INNATE IMMUNE-RESPONSE  VARICELLA-ZOSTER-VIRUS  SIGNALING PATHWAY  PROTEIN-KINASE  HORIZONTAL TRANSFER  INHIBITION  EVOLUTION  GENE  HERPESVIRUSES   Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures 期刊论文 CELL RESEARCH, 2017 Peng, Ruchao; Xu, Ying; Zhu, Tengfei; Li, Ningning; Qi, Jianxun; Chai, Yan; Wu, Min; Zhang, Xinzheng; Shi, Yi; Wang, Peiyi; Wang, Jiawei; Gao, Ning; Gao, George Fu 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 CRISPR/Cas system  anti-CRISPR proteins  phage  immune evasion  cryo-EM  BACTERIAL IMMUNE-SYSTEM  VIBRIO-PARAHAEMOLYTICUS  BACTERIOPHAGE THERAPY  ELECTRON-MICROSCOPY  ESCHERICHIA-COLI  CAS SYSTEMS  DNA  MECHANISMS  CASCADE  CRYSTALLOGRAPHY   STING-mediated DNA sensing in cancer immunotherapy 期刊论文 SCIENCE CHINA-LIFE SCIENCES, 2017 Zhou, Xiang; Jiang, Zhengfan 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 cancer immunotherapy  cGAS  innate immunity  STING  tumorigenesis  type I interferon  CYCLIC GMP-AMP  INNATE IMMUNE RECOGNITION  I IFN SIGNALS  C-DI-GMP  CYTOSOLIC DNA  ANTITUMOR IMMUNITY  5,6-DIMETHYLXANTHENONE-4-ACETIC ACID  TUMOR MICROENVIRONMENT  BACTERIAL 2ND-MESSENGER  IMMUNOGENIC TUMORS