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科研机构
上海药物研究所 [7]
复旦大学上海医学院 [3]
兰州大学 [1]
中国科学院大学 [1]
上海中医药大学 [1]
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期刊论文 [15]
发表日期
2016 [15]
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Behavioral... [1]
Neuroscien... [1]
Psychology [1]
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Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Effects of the cannabinoid 1 receptor peptide ligands hemopressin, (m)RVD-hemopressin(alpha) and (m)VD-hemopressin(alpha) on memory in novel object and object location recognition tasks in normal young and Abeta1-42-treated mice.
期刊论文
NEUROBIOLOGY OF LEARNING AND MEMORY, 2016, 卷号: 134, 页码: 264-274
作者:
Zhang, Rui-San
;
He, Zhen
;
Jin, Wei-Dong
;
Wang, Rui
;
Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2017/01/10
Cannabinoid receptor
Hemopressin
(m)RVD-hemopressin(alpha)
(m)VD-hemopressin(alpha)
Recognition memory
Alzheimer's disease
Mglur1 and mglur5 synergistically control cholinergic synaptic transmission in the thalamic reticular nucleus
期刊论文
Journal of neuroscience, 2016, 卷号: 36, 期号: 30, 页码: 7886-7896
作者:
Sun, Yan-Gang
;
Rupprecht, Vanessa
;
Zhou, Li
;
Dasgupta, Rajan
;
Seibt, Frederik
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  |  
浏览/下载:28/0
  |  
提交时间:2019/05/09
Acetylcholine
Basal forebrain
Long-term plasticity
Metabotropic glutamate receptor
Synergistic
Thalamic reticular nucleus
Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 13, 页码: 6329-6343
作者:
Sun, Hao
;
Shi, Min
;
Zhang, Wei
;
Zheng, Yue-Ming
;
Xu, Ya-Zhou
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
The anxiolytic- and antidepressant-like effects of ATPM-ET, a novel kappa agonist and mu partial agonist, in mice
期刊论文
PSYCHOPHARMACOLOGY, 2016, 卷号: 233, 期号: 12, 页码: 2411-2418
作者:
Wang, Qian
;
Long, Yu
;
Hang, Ai
;
Zan, Gui-Ying
;
Shu, Xiao-Hong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
ATPM-ET
Emotional response
kappa agonist
mu partial agonist
Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant Activity
期刊论文
CNS NEUROSCIENCE & THERAPEUTICS, 2016, 卷号: 22, 期号: 5, 页码: 368-377
作者:
Wang, Yun
;
Guo, Lin
;
Jiang, Hua-Feng
;
Zheng, Long-Tai
;
Zhang, Ao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Allosteric modulation
Antidepressant
Brain-derived neurotrophic factor
Glycogen synthase kinase 3
Sigma-1 receptors
Discovery and Characterization of a Novel Small-Molecule Agonist for Medium-Chain Free Fatty Acid Receptor G Protein-Coupled Receptor 84
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2016, 卷号: 357, 期号: 2, 页码: 337-344
作者:
Zhang, Qing
;
Yang, Hui
;
Li, Jing
;
Xie, Xin
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Discovery of Potent and Selective Agonists of delta Opioid Receptor by Revisiting the "Message-Address" Concept
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 7, 期号: 4, 页码: 391-396
作者:
Shen, Qing
;
Qian, Yuanyuan
;
Huang, Xiaoqin
;
Xu, Xuejun
;
Li, Wei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
delta opioid receptor
agonist
affinity
selectivity
molecular docking
Reducing central serotonin in adulthood promotes hippocampal neurogenesis
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Song, Ning-Ning
;
Jia, Yun-Fang
;
Zhang, Lei
;
Zhang, Qiong
;
Huang, Ying
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Role of estrogen receptor beta selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis
期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 卷号: 22, 期号: 18
作者:
Zhang, Cheng-Gang
;
Zhang, Bin
;
Deng, Wen-Sheng
;
Duan, Ming
;
Chen, Wei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Portal hypertension
Estrogen receptor
Rho-kinase signaling
Nitric oxide
Hepatic stellate cells
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