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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [17]
发表日期
2016 [17]
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浏览/检索结果:
共17条,第1-10条
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发表日期:2016
专题:上海药物研究所
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Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells
期刊论文
FRONTIERS IN PHYSIOLOGY, 2016, 卷号: 7
作者:
Yu, Chengli
;
Gao, Jing
;
Zhou, Yanting
;
Chen, Xiangling
;
Xiao, Ruoxuan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
phosphoproteomics
Alzheimer's disease
drug effect
mass spectrometry
neutronal cells
A redox mechanism underlying nucleolar stress sensing by nucleophosmin
期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:
Yang, Kai
;
Wang, Ming
;
Zhao, Yuzheng
;
Sun, Xuxu
;
Yang, Yi
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1391-1400
作者:
Tao, Ling-xue
;
Huang, Xiao-tian
;
Chen, Yu-ting
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
iron
reactive oxygen species
mitochondria dysfunction
acetylcholinesterase
Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H2O2-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1413-1422
作者:
Yu, Bang-wei
;
Li, Jin-long
;
Guo, Bin-bin
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
chlorogenic acid analogues
Gynura nepalensis
cardiomyocytes
oxidative stress
ROS
apoptosis
epigallocatechin gallate
ERK/JNK pathway
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343)
streptozotocin
amyloid beta
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury
期刊论文
FASEB JOURNAL, 2016, 卷号: 30, 期号: 7, 页码: 2500-2510
作者:
Chen, Weimin
;
Li, Shanshan
;
Li, Jinwei
;
Zhou, Wen
;
Wu, Shouhai
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Nrf2 activator
Keap1-Nrf2 pathway
oxidative damage
Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 21, 页码: 11083-11093
作者:
Li, Qi
;
Huang, Yue
;
Liu, Xichun
;
Gan, Jianhua
;
Chen, Hao
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
bacteria
cancer therapy
chemical biology
DNA repair
DNA-protein interaction
enzyme inhibitor
enzyme structure
Salvianolic acid A inhibits endothelial dysfunction and vascular remodeling in spontaneously hypertensive rats
期刊论文
LIFE SCIENCES, 2016, 卷号: 144, 页码: 86-93
作者:
Teng, Fukang
;
Yin, Ying
;
Cui, Yajun
;
Deng, Yanping
;
Li, Defang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Salvianolic acid A
Hypertension
Microvascular remodeling
Spontaneously hypertensive rats
Vascular endothelial function
Protective effects of beta-dihydroagarofuran-type sesquiterpene against Abeta_(25-35)-induced neuronal apoptosis and oxidative damage
期刊论文
Journal of Chinese Pharmaceutical Sciences, 2016, 卷号: 25, 期号: 8, 页码: 582-589
作者:
Ji SS(冀莎莎)
;
Lei Y(雷芸)
;
Huang XT(黄霄天)
;
Gao ZQ(高志芹)
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Abeta
Neuroprotection
Apoptosis
Oxidative stress
NMR-based metabolomic investigation of regional brain tissue dysfunctions of MCAO rats induced by ischemia
期刊论文
Journal of China Pharmaceutical University, 2016, 卷号: 47, 期号: 2, 页码: 188-198
作者:
Zhang Tianshu
;
Ruan Zhi
;
Liu Xia
;
Huang Jin
;
Zhang Naixia
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
NMR
metabolomics
ischemia and reperfusion
stroke
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