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科研机构
上海药物研究所 [125]
内容类型
期刊论文 [121]
会议论文 [4]
发表日期
2016 [125]
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发表日期:2016
专题:上海药物研究所
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Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 52, 页码: 26722-26738
作者:
Hu, Hao
;
Luo, Cheng
;
Zheng, Y. George
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis
期刊论文
CELL RESEARCH, 2016, 卷号: 26, 期号: 12, 页码: 1330-1344
作者:
Zhang, Lin
;
Xiao, Jianfeng
;
Xu, Jianrong
;
Fu, Tianran
;
Cao, Zhiwei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
fatty acid biosynthesis
dehydratase
ACP
complex structure
Characterization of Protein Lysine Propionylation in Escherichia coli: Global Profiling, Dynamic Change, and Enzymatic Regulation
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2016, 卷号: 15, 期号: 12, 页码: 4696-4708
作者:
Sun, Mingwei
;
Xu, Junyu
;
Wu, Zhixiang
;
Zhai, Linhui
;
Liu, Chengxi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
post-translational modification(s)
lysine propionylation
SILAC
CobB
PatZ
Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 23, 页码: 6206-6214
作者:
Zhang, Jiankang
;
Gao, Lixin
;
Xi, Jianjun
;
Sheng, Li
;
Zhao, Yanmei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Proteasome inhibitors
Piperidine
Non-covalent
Anti-cancer
SARs
Antitumor effect of dobutamine on multiple myeloma via mitogen-activated protein kinase pathway in vitro
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2016, 卷号: 48, 期号: 12, 页码: 1135-1137
作者:
Xie, Bingqian
;
Xu, Zhijian
;
Yang, Guang
;
Chen, Gege
;
Li, Bo
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Identification of compound-protein interactions through the analysis of gene ontology, KEGG enrichment for proteins and molecular fragments of compounds
期刊论文
MOLECULAR GENETICS AND GENOMICS, 2016, 卷号: 291, 期号: 6, 页码: 2065-2079
作者:
Chen, Lei
;
Zhang, Yu-Hang
;
Zheng, Mingyue
;
Huang, Tao
;
Cai, Yu-Dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Compound-protein interaction
Gene ontology enrichment
KEGG enrichment
Minimum redundancy maximum relevance
Incremental feature selection
Staurosporine as an agonist for induction of GLUT4 translocation, identified by a pH-sensitive fluorescent IRAP-mOrange2 probe
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 480, 期号: 4, 页码: 534-538
作者:
Li, Yufeng
;
Zheng, Li
;
Wang, Dan
;
Zhang, Xiang
;
Li, Jia
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Diabetes
pH-sensitive fluorescent probe
GLUT4 translocation
Staurosporine
Insulin additive analogue
An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain
期刊论文
CELL DISCOVERY, 2016, 卷号: 2
作者:
Yin, Yanting
;
Zhou, X. Edward
;
Hou, Li
;
Zhao, Li-Hua
;
Liu, Bo
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
GLP-1R
class B GPCR
intrinsic agonist
glucagon-like peptide-1
exendin-4
BETP
Comparative pharmacokinetic analysis of extracts of crude and wine-processed Dipsacus asper in rats by a sensitive ultra performance liquid chromatography-tandem mass spectrometry approach
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1036, 页码: 33-41
作者:
Tao, Yi
;
Ren, Yuchao
;
Li, Weidong
;
Cai, Baochang
;
Di, Liuqing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Dipsacus asper
Wine-processed
UPLC-MS/MS
Pharmacokinetics
Enhanced conformational sampling technique provides an energy landscape view of large-scale protein conformational transitions
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 卷号: 18, 期号: 42, 页码: 29170-29182
作者:
Shao, Qiang
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  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
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