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期刊论文 [30]
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2013 [30]
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Pharmacol... [30]
Chemistry [7]
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发表日期:2013
学科主题:Pharmacology & Pharmacy
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Identification of two novel inhibitors of mTOR signaling pathway based on high content screening
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:
Yan, Juming
;
Zhou, Hongyu
;
Kong, Lingmei
;
Zhang, Jing
;
Zhao, Qinshi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2013/11/12
mTOR signaling
Inhibitor
High content screening
Cancer
Apoptosis
Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44
期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 8, 页码: 3068-3076
作者:
Li, Chun-Shun
;
Li, Xiao-Ming
;
Gao, Shu-Shan
;
Lu, Yan-Hua
;
Wang, Bin-Gui
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  |  
浏览/下载:23/0
  |  
提交时间:2014/07/17
marine fungus
sediment
anthranilic acid
Penicillium paneum
cytotoxicity
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:
Jiang, Bo
;
Guo, Shuju
;
Shi, Dayong
;
Guo, Chao
;
Wang, Tao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2014/07/17
Type 2 diabetes mellitus
Protein tyrosine phosphatase 1B
Bromophenol
Anti-diabetic activities
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:
Geng, Chang-An
;
Wang, Li-Jun
;
Guo, Rui-Hua
;
Chen, Ji-Jun
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  |  
浏览/下载:21/0
  |  
提交时间:2013/06/08
Hepatitis B virus (HBV)
small-molecule inhibitors
nucleoside analogs
non-nucleosides
natural products
synthesized compounds
chemical modification
patents
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice
期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:
Shi, Dayong
;
Guo, Shuju
;
Jiang, Bo
;
Guo, Chao
;
Wang, Tao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2014/07/17
bromophenol
protein tyrosine phosphatase 1B inhibitor
db/db mouse model
anti-diabetes properties
Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 17, 页码: 4944-4947
作者:
Gong Xudong
;
Wang Guan
;
Ren Jing
;
Liu Zheng
;
Wang Zhen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2013/11/07
PDE5 inhibitors
5-Bromopyrimidin-4(3H)-ones
A new family of cystine knot peptides from the seeds of Momordica cochinchinensis
期刊论文
PEPTIDES, 2013, 卷号: 39, 页码: 29-35
作者:
Chan, Lai Yue
;
He, Wenjun
;
Tan, Ninghua
;
Zeng, Guangzhi
;
Craik, David J.
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  |  
浏览/下载:30/0
  |  
提交时间:2013/07/24
Cystine Knot
Peptides
Mco-3 To Mco-6
Momordica Cochinchinensis
Novel Hybrids of (Phenylsulfonyl)furoxan and Anilinopyrimidine as Potent and Selective Epidermal Growth Factor Receptor Inhibitors for Intervention of Non-Small-Cell Lung Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4738-4748
作者:
Han, C
;
Huang, ZJ
;
Zheng, C
;
Wan, LD
;
Zhang, LW
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2015/07/22
Nitric oxide donating anilinopyrimidines: Synthesis and biological evaluation as EGFR inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 期号: 1, 页码: 82-90
作者:
Han, C
;
Huang, ZJ
;
Zheng, C
;
Wan, LD
;
Lai, YS
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2015/07/22
Nitric oxide
EGFR inhibitor
Anilinopyrimidine
Antiproliferative activity
WZ4002
Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 20
Zhou, Wei
;
Liu, Xiaofeng
;
Tu, Zhengchao
;
Zhang, Lianwen
;
Ku, Xin
;
Bai, Fang
;
Zhao, Zhenjiang
;
Xu, Yufang
;
Ding, Ke
;
Li, Honglin
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  |  
浏览/下载:16/0
  |  
提交时间:2016/12/16
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