Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures

	Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures
	Sang, Li 2; Qin, Wen 2; Liu, Yong1 ; Han, Wei 2; Zhang, Yunting 2; Jiang, Tianzi1 ; Yu, Chunshui 2,3
刊名	NEUROIMAGE
	2012-07-16
卷号	61 期号:4 页码:1213-1225
关键词	Cerebellum Subregions Functional connectivity Resting-state Magnetic resonance imaging
英文摘要	The human cerebellum is a heterogeneous structure, and the pattern of resting-state functional connectivity (rsFC) of each subregion has not yet been fully characterized. We aimed to systematically investigate rsFC pattern of each cerebellar subregion in 228 healthy young adults. Voxel-based analysis revealed that several subregions showed similar rsFC patterns, reflecting functional integration; however, different subregions displayed distinct rsFC patterns, representing functional segregation. The same vermal and hemispheric subregions showed either different patterns or different strengths of rsFCs with the cerebrum, and different subregions of lobules VII and VIII displayed different rsFC patterns. Region of interest (ROI)-based analyses also confirmed these findings. Specifically, strong rsFCs were found: between lobules I-VI and vermal VIIb-IX and the visual network; between hemispheric VI, VIIb, VIIIa and the auditory network; between lobules I-VI, VIII and the sensorimotor network; between lobule IX, vermal VIIIb and the default-mode network; between lobule Crus I, hemispheric Crus II and the fronto-parietal network; between hemispheric VIIb, VIII and the task-positive network; between hemispheric VI, VIIb, VIII and the salience network; between most cerebellar subregions and the thalamus; between lobules V, VIIb and the midbrain red nucleus; between hemispheric Crus I, Crus II, vermal VIIIb, IX and the caudate nucleus; between lobules V, VI, VIIb, VIIIa and the pallidum and putamen; and between lobules I-V, hemispheric VIII, IX and the hippocampus and amygdala. These results confirm the existence of both functional integration and segregation among cerebellar subregions and largely improve our understanding of the functional organization of the human cerebellum. (C) 2012 Elsevier Inc. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]	HUMAN RED NUCLEUS ; VERBAL WORKING-MEMORY ; LEG WITHDRAWAL REFLEX ; MEDIAL TEMPORAL-LOBE ; HUMAN BRAIN ; CEREBROCEREBELLAR NETWORK ; PREFRONTAL CORTEX ; ALE METAANALYSIS ; TUMOR RESECTION ; BASAL GANGLIA
收录类别	SCI
语种	英语
WOS记录号	WOS:000305920600047
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/3166]
专题	自动化研究所_脑网络组研究中心
作者单位	1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, LIAMA Ctr Computat Med, Beijing 100190, Peoples R China 2.Tianjin Med Univ, Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China 3.Tianjin Med Univ, Sch Med Imaging, Tianjin 300052, Peoples R China
推荐引用方式 GB/T 7714	Sang, Li,Qin, Wen,Liu, Yong,et al. Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures[J]. NEUROIMAGE,2012,61(4):1213-1225.
APA	Sang, Li.,Qin, Wen.,Liu, Yong.,Han, Wei.,Zhang, Yunting.,...&Yu, Chunshui.(2012).Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures.NEUROIMAGE,61(4),1213-1225.
MLA	Sang, Li,et al."Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures".NEUROIMAGE 61.4(2012):1213-1225.