Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan
Yang, Qi1,2; Han, Jiancheng1,2; Wang, Rui1,2; Zhang, Tong3; Zhang, Yingying1,2; Wang, Jingyi1,2; Xu, Lei1,2; Hou, Zengguang4; Wang, Shuangyi4; He, Yihua1,2
刊名BIOENGINEERING-BASEL
2022-10-01
卷号9期号:10页码:9
关键词congenital heart disease fetal echocardiography digital twin cardiovascular casting virtual ultrasound
DOI10.3390/bioengineering9100524
通讯作者Wang, Shuangyi(shuangyi.wang@ia.ac.cn) ; He, Yihua(heyihuaecho@hotmail.com)
英文摘要Despite recent breakthroughs in diagnosis and treatment, congenital heart defects (CHDs) continue to be the leading cause of death among newborns. Fetal echocardiography is the most effective and non-invasive method for the prenatal diagnosis of CHDs. However, the challenge of obtaining standard views can lead to a low diagnostic accuracy. To explore new methods for training, the combined use of cardiovascular casting, computed tomography (CT) scanning, and virtual ultrasound generation methods was studied to preserve the cardiac structures of a fetus in digital form. The feasibility of the proposed workflow was verified by testing three fetal heart specimens collected after the termination of pregnancy. As a result, the anatomical structures were imaged clearly by a CT scan after cardiovascular casting, and the virtually generated ultrasound images based on the use of the Public software Library for UltraSound imaging research (PLUS) toolkit successfully demonstrated both the standard views and the views with diagnostic values for the visualization of the cardiovascular structures. This solution provides great data extensibility while being simple and cost-effective for end users. Therefore, the proposed method could provide a promising educational system for trainees to understand standard views of fetal echocardiography and the corresponding anatomical correlations.
资助项目National Natural Science Foundation of China[U21A20523] ; National Natural Science Foundation of China[62003339]
WOS研究方向Biotechnology & Applied Microbiology ; Engineering
语种英语
出版者MDPI
WOS记录号WOS:000872284800001
资助机构National Natural Science Foundation of China
内容类型期刊论文
源URL[http://ir.ia.ac.cn/handle/173211/50526]  
专题自动化研究所_复杂系统管理与控制国家重点实验室_先进机器人控制团队
通讯作者Wang, Shuangyi; He, Yihua
作者单位1.Beijing Anzhen Hosp, Maternal Fetal Med Ctr Fetal Heart Dis, Beijing 100029, Peoples R China
2.Capital Med Univ, Beijing Anzhen Hosp, Echocardiog Med Ctr, Beijing 100029, Peoples R China
3.Peng Cheng Lab PCL, Dept Network Intelligence, Shenzhen 518055, Peoples R China
4.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Yang, Qi,Han, Jiancheng,Wang, Rui,et al. Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan[J]. BIOENGINEERING-BASEL,2022,9(10):9.
APA Yang, Qi.,Han, Jiancheng.,Wang, Rui.,Zhang, Tong.,Zhang, Yingying.,...&He, Yihua.(2022).Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan.BIOENGINEERING-BASEL,9(10),9.
MLA Yang, Qi,et al."Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan".BIOENGINEERING-BASEL 9.10(2022):9.
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