Sex-related Difference in Mental Rotation Performance is Mediated by the special Functional Connectivity Between the Default Mode and Salience Networks

doi:10.1016/j.neuroscience.2021.10.009

	Sex-related Difference in Mental Rotation Performance is Mediated by the special Functional Connectivity Between the Default Mode and Salience Networks
	Long, Haixia 9; Fan, Ming 8; Yang, Xuhua 9; Guan, Qiu 9; Huang, Yujiao 7; Xu, Xinli 9; Xiao, Jie 9; Jiang, Tianzi 1,2,3,4,5,6
刊名	NEUROSCIENCE
	2021-12-01
卷号	478 页码:65-74
关键词	sex difference mental rotation default mode network salience network functional connectivity mediation analysis
ISSN号	0306-4522
DOI	10.1016/j.neuroscience.2021.10.009
通讯作者	Jiang, Tianzi(jiangtz@nlpr.ia.ac.cn)
英文摘要	mental rotation task is a particular spatial skill that helps people process visual information and is associated with intelligence and academic performance. Previous studies have found consistent sex difference in mental rotation. However, the neural mechanism of the sex-related difference in mental rotation remains unclear. This study investigates the association between sex, mental rotation and the functional connectivity (FC) of resting-state networks (RSNs) to explore neural correlates of different mental rotation abilities between males and females. Compared with females, males performed better on the mental rotation test. The mental rotation scores were significantly correlated with the special FC between the default mode network (DMN) and salience network (SN). The results of the mediation analysis revealed that the special FC between the DMN and SN mediated the association between sex and mental rotation. Based on these findings, males had higher FC between the DMN and SN, which subsequently promoted their mental rotation performance. These results emphasized the importance of sex in spatial cognition studies of both healthy people and individuals with neuropsychiatric disorders and deepened our understanding of the neural mechanisms underlying sex difference in mental rotation. (c) 2021 IBRO. Published by Elsevier Ltd. All rights reserved.
资助项目	National Natural Science Foundation of China[61773348] ; National Natural Science Foundation of China[61871428] ; National Natural Science Foundation of China[61972354] ; National Natural Science Foundation of China[U20A20171] ; Zhejiang Provincial Natural Science Foundation of China[LQ18F030015] ; Zhejiang Provincial Natural Science Foundation of China[LY18F030023] ; Zhejiang Provincial Natural Science Foundation of China[LY21F020027] ; Public Welfare Technology Research Project in Zhe'jiang Province of China[LGG20F020017]
WOS关键词	INTRAPARIETAL SULCUS ; BRAIN NETWORKS ; GLOBAL SIGNAL ; METAANALYSIS ; STRATEGIES ; HEMISPHERE ; REST
WOS研究方向	Neurosciences & Neurology
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000719237600002
资助机构	National Natural Science Foundation of China ; Zhejiang Provincial Natural Science Foundation of China ; Public Welfare Technology Research Project in Zhe'jiang Province of China
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/46461]
专题	自动化研究所_脑网络组研究中心
通讯作者	Jiang, Tianzi
作者单位	1.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing 100190, Peoples R China 2.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia 3.Univ Elect Sci & Technol China, Chengdu Brain Sci Inst, MOE Key Lab Neuroinformat, Clin Hosp, Chengdu 625014, Peoples R China 4.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Automat, Beijing 100190, Peoples R China 5.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100049, Peoples R China 6.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China 7.Zhejiang Univ Technol, Zhijiang Coll, Hangzhou 310024, Peoples R China 8.Hangzhou Dianzi Univ, Inst Biomed Engn & Instrumentat, Hangzhou 310018, Zhejiang, Peoples R China 9.Zhejiang Univ Technol, Coll Comp Sci & Technol, Hangzhou 310023, Peoples R China
推荐引用方式 GB/T 7714	Long, Haixia,Fan, Ming,Yang, Xuhua,et al. Sex-related Difference in Mental Rotation Performance is Mediated by the special Functional Connectivity Between the Default Mode and Salience Networks[J]. NEUROSCIENCE,2021,478:65-74.
APA	Long, Haixia.,Fan, Ming.,Yang, Xuhua.,Guan, Qiu.,Huang, Yujiao.,...&Jiang, Tianzi.(2021).Sex-related Difference in Mental Rotation Performance is Mediated by the special Functional Connectivity Between the Default Mode and Salience Networks.NEUROSCIENCE,478,65-74.
MLA	Long, Haixia,et al."Sex-related Difference in Mental Rotation Performance is Mediated by the special Functional Connectivity Between the Default Mode and Salience Networks".NEUROSCIENCE 478(2021):65-74.