Muscle Fatigue in Response to Electrical Stimulation Pattern and Frequency in Spinal Cord Injury

doi:10.1002/pmrj.12282

CORC > 自动化研究所 > 中国科学院自动化研究所 > 类脑智能研究中心 > 神经计算及脑机交互

	Muscle Fatigue in Response to Electrical Stimulation Pattern and Frequency in Spinal Cord Injury
	Qiu, Shuang 1,2,3; Draghici, Adina E.1,3; Picard, Glen 3; Taylor, J. Andrew 1,3
刊名	PM&R
	2019-12-12
页码	7
ISSN号	1934-1482
DOI	10.1002/pmrj.12282
通讯作者	Taylor, J. Andrew(jandrew_taylor@hms.harvard.edu)
英文摘要	Background Functional electrical stimulation (FES) is widely used to induce functional movements for paralyzed muscles. However, rapid muscle fatigue during FES-induced muscle contractions limits FES clinical efficacy. Objective To investigate muscle fatigue response across stimulation patterns and frequencies during FES in able-bodied individuals and in those with spinal cord injury (SCI). Design Four stimulation protocols combining 20 and 40 Hz average frequency with either constant frequency trains (CFTs) or with doublet frequency trains (DFTs) were applied to the quadriceps of seven adults with SCI and eight able-bodied participants. Setting A FES-row training laboratory. Participants Seven individuals with SCI (one female; age range, 25 +/- 6 years) and eight age-matched able-bodied participants (one female). Intervention None. Main Outcome Measures Fatigue was defined as the number of contractions until force decreased by 20% from the target level of 25% maximal contraction force. The number of contractions and the stimulation current used during the four stimulation protocols were compared. Results There was a significant effect of frequency, as well as interaction between group and stimulation pattern (P < .05). In both groups, 20-Hz trains increased the number of contractions to fatigue compared to 40-Hz trains. However, the responses to the pattern of stimulation differed. In the able-bodied participants, CFT increased the number of contractions to fatigue compared to DFT, whereas in those with SCI, DFT increased the number of contractions to fatigue. In fact, DFT resulted in similar number of contractions to fatigue in both populations. Conclusions These results indicate that DFT at 20 Hz may be a better stimulation protocol to delay fatigue onset in the SCI population than the other three protocols. In addition, this work implies that results from able-bodied persons may not be directly applicable to those with SCI.
资助项目	National Institutes of Health[HL117037] ; China Scholarship Council
WOS关键词	HUMAN SKELETAL-MUSCLE ; QUADRICEPS FEMORIS MUSCLE ; IMPROVES PERFORMANCE ; ISOMETRIC FORCE ; INDIVIDUALS ; RECRUITMENT ; ADAPTATIONS ; ACTIVATION ; STRATEGIES ; PARAMETERS
WOS研究方向	Rehabilitation ; Sport Sciences
语种	英语
出版者	WILEY
WOS记录号	WOS:000502743000001
资助机构	National Institutes of Health ; China Scholarship Council
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/29431]
专题	类脑智能研究中心_神经计算及脑机交互
通讯作者	Taylor, J. Andrew
作者单位	1.Harvard Med Sch, Dept Phys Med & Rehabil, Cambridge, MA USA 2.Chinese Acad Sci, Res Ctr Brain Inspired Intelligence, Inst Automat, Beijing, Peoples R China 3.Spaulding Hosp Cambridge, Cardiovasc Res Lab, Cambridge, MA 02138 USA
推荐引用方式 GB/T 7714	Qiu, Shuang,Draghici, Adina E.,Picard, Glen,et al. Muscle Fatigue in Response to Electrical Stimulation Pattern and Frequency in Spinal Cord Injury[J]. PM&R,2019:7.
APA	Qiu, Shuang,Draghici, Adina E.,Picard, Glen,&Taylor, J. Andrew.(2019).Muscle Fatigue in Response to Electrical Stimulation Pattern and Frequency in Spinal Cord Injury.PM&R,7.
MLA	Qiu, Shuang,et al."Muscle Fatigue in Response to Electrical Stimulation Pattern and Frequency in Spinal Cord Injury".PM&R (2019):7.