High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations

doi:10.1016/j.cmpb.2020.105598

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations
	Hong, Qingqi 2; Li, Qingde 1; Wang, Beizhan 2; Tian, Jie 3; Xu, Fei 2; Liu, Kunhong 2; Cheng, Xuan 2
刊名	COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
	2020-11-01
卷号	196 页码:13
关键词	Geometric modeling Vascular visualization Implicit functions Blood flow simulation Extrusion surfaces
ISSN号	0169-2607
DOI	10.1016/j.cmpb.2020.105598
通讯作者	Liu, Kunhong(lkhqz@xmu.edu.cn) ; Cheng, Xuan(21408732@qq.com)
英文摘要	Background and Objective: High-quality vascular modeling is crucial for blood flow simulations, i.e., computational fluid dynamics (CFD). As without an accurate geometric representation of the smooth vascular surface, it is impossible to make meaningful blood flow simulations. The purpose of this work is to develop high-quality vascular modeling and modification method for blood flow computations. Methods: We develop a new technique for the accurate geometric modeling and modification of vasculatures using implicit extrusion surfaces (IES). In the proposed method, the skeleton of the vascular structure is subdivided into short curve segments, each of which is then represented implicitly locally as the intersection of two mutually orthogonal implicit surfaces defined by distance functions. A set of contour points is extracted and fitted with an implicit curve for accurately specifying the vessel cross-section profile, which is then extruded locally along the skeleton to fill the gaps between two vascular tube cross sections. We also present a new implicit geometric editing technique to modify the constructed vascular model with pathology for virtual stenting. Results: Experimental results and validations show that accurate vascular models with highly smooth surfaces can be generated by the proposed method. In addition, we conduct some blood flow simulations to indicate the effectiveness of proposed method for hemodynamic simulations. Conclusions: The proposed technique can achieve precise geometric models of vasculatures with any required degree of smoothness for reliable blood flow simulations. (C) 2020 Elsevier B.V. All rights reserved.
资助项目	National Natural Science Foundation of China[61502402] ; National Natural Science Foundation of China[61,772,023] ; National Natural Science Foundation of China[61802322] ; Fundamental Research Funds for the Central Universities[20720180073] ; Fundamental Research Funds for the Central Universities[20720190003] ; National Key RD Program of China[2019QY1803]
WOS关键词	VISUALIZATION ; SIMULATION ; RECONSTRUCTION ; SEGMENTATION ; ANGIOGRAPHY ; VALIDATION
WOS研究方向	Computer Science ; Engineering ; Medical Informatics
语种	英语
出版者	ELSEVIER IRELAND LTD
WOS记录号	WOS:000580609200027
资助机构	National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; National Key RD Program of China
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/41736]
专题	自动化研究所_中国科学院分子影像重点实验室
通讯作者	Liu, Kunhong; Cheng, Xuan
作者单位	1.Univ Hull, Sch Engn & Comp Sci, Kingston Upon Hull, N Humberside, England 2.Xiamen Univ, Sch Informat, Xiamen, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Hong, Qingqi,Li, Qingde,Wang, Beizhan,et al. High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations[J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,2020,196:13.
APA	Hong, Qingqi.,Li, Qingde.,Wang, Beizhan.,Tian, Jie.,Xu, Fei.,...&Cheng, Xuan.(2020).High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations.COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,196,13.
MLA	Hong, Qingqi,et al."High-quality vascular modeling and modification with implicit extrusion surfaces for blood flow computations".COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 196(2020):13.