NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic | |
Hu, Zhenhua6,7; Chen, Wen-Hua1,4,5; Tian, Jie2,3,6,7; Cheng, Zhen4,5 | |
刊名 | TRENDS IN MOLECULAR MEDICINE |
2020-05-01 | |
卷号 | 26期号:5页码:469-482 |
ISSN号 | 1471-4914 |
DOI | 10.1016/j.molmed.2020.02.003 |
通讯作者 | Tian, Jie(jie.tian@ia.ac.cn) ; Cheng, Zhen(zcheng@stanford.edu) |
英文摘要 | Near-IR fluorescence imaging (NIRFI) is a highly promising technique for improving cancer theranostics in the era of precision medicine. Through the combination with cutting-edge bionanotechnologies, the potential of NIRFI can be greatly broadened. A variety of novel NIRF nanoprobes has been developed with ultimate goals of addressing unmet medical needs. Here, we present recent breakthroughs on the fundamental aspects of NIRFI, such as imaging at long wavelengths (1000-1700 nm), and the use of new approaches (X-rays, chemiluminescence, radioluminescence, etc.) for the excitation of novel nanoprobes. Within two decades, research on NIRF nanoprobes has translated to clinical trials and it will further translate to cancer management. |
资助项目 | National Key Research and Development Program of China[2017YFA0205200] ; National Key Research and Development Program of China[2016YFC0102600] ; National Natural Science Foundation of China (NSFC)[21877057] ; National Natural Science Foundation of China (NSFC)[81930053] ; National Natural Science Foundation of China (NSFC)[61622117] ; Beijing Nova Program[Z181100006218046] ; Jiangmen Program for Innovative Research Team[2018630100180019806] ; Department of Radiology, Stanford University |
WOS关键词 | IN-VIVO ; CERENKOV RADIATION ; FLUORESCENCE ; NANOPARTICLES ; LUMINESCENCE ; AFTERGLOW ; WINDOW ; NANOPHOSPHORS ; THERANOSTICS ; MODALITIES |
WOS研究方向 | Biochemistry & Molecular Biology ; Cell Biology ; Research & Experimental Medicine |
语种 | 英语 |
出版者 | ELSEVIER SCI LTD |
WOS记录号 | WOS:000532705900005 |
资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China (NSFC) ; Beijing Nova Program ; Jiangmen Program for Innovative Research Team ; Department of Radiology, Stanford University |
内容类型 | 期刊论文 |
源URL | [http://ir.ia.ac.cn/handle/173211/39438] |
专题 | 自动化研究所_中国科学院分子影像重点实验室 |
通讯作者 | Tian, Jie; Cheng, Zhen |
作者单位 | 1.Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China 2.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Beijing 100191, Peoples R China 3.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Peoples R China 4.Stanford Univ, Sch Med, Stanford Canc Ctr, Stanford, CA 94305 USA 5.Stanford Univ, Sch Med, Dept Radiol, Bio X Program,MIPS, Stanford, CA 94305 USA 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Chinese Acad Sci, CAS Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Inst Automat,Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Hu, Zhenhua,Chen, Wen-Hua,Tian, Jie,et al. NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic[J]. TRENDS IN MOLECULAR MEDICINE,2020,26(5):469-482. |
APA | Hu, Zhenhua,Chen, Wen-Hua,Tian, Jie,&Cheng, Zhen.(2020).NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic.TRENDS IN MOLECULAR MEDICINE,26(5),469-482. |
MLA | Hu, Zhenhua,et al."NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic".TRENDS IN MOLECULAR MEDICINE 26.5(2020):469-482. |
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