Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation

doi:10.1016/j.neulet.2019.134289

	Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation
	Liu, Haiyang 1; Jian, Minyu 1; Liu, Shu 2; Li, Ang 2; Li, Shaowu 3; Fang, Jinghan 1; Liang, Fa 1; Liu, Bing 2; Han, Ruquan 1
刊名	NEUROSCIENCE LETTERS
	2019-08-10
卷号	707 页码:7
关键词	Functional connectivity Sedation Dexmedetomidine Resting state Functional magnetic resonance Imaging
ISSN号	0304-3940
DOI	10.1016/j.neulet.2019.134289
通讯作者	Han, Ruquan(ruquan.han@ccmu.edu.cn)
英文摘要	Functional connectivity patterns of the human brain show unique inherent or intrinsic characteristics at rest and when performing a task, similar to a fingerprint. However, whether this unique functional organization is preserved during sedation currently remains unknown. Here, we collected resting-state functional magnetic resonance imaging data from 20 subjects in each of three resting states: wakefulness, sedation, and recovery. We found that functional connectivity patterns could successfully identify individual subjects in any pair of the three resting states. In particular, identification analysis using functional connectivity patterns based on the frontoparietal network showed the highest success rates. Moreover, the overall individual difference in the frontoparietal-based functional connectivity patterns was much larger than that derived from other networks in each resting state. Collectively, our findings indicate that functional connectivity patterns within individual subjects are unique and relatively robust to brain state changes, regardless of dexmedetomidine-induced sedation.
WOS关键词	FINGERPRINTING IDENTIFYING INDIVIDUALS ; PROPOFOL-INDUCED LOSS ; STATE
WOS研究方向	Neurosciences & Neurology
语种	英语
出版者	ELSEVIER IRELAND LTD
WOS记录号	WOS:000486094600001
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/26989]
专题	中国科学院自动化研究所
通讯作者	Han, Ruquan
作者单位	1.Capital Med Univ, Beijing Tiantan Hosp, Dept Anesthesiol, Beijing, Peoples R China 2.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 3.Beijing Neurosurg Inst, Funct Imaging Ctr, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Liu, Haiyang,Jian, Minyu,Liu, Shu,et al. Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation[J]. NEUROSCIENCE LETTERS,2019,707:7.
APA	Liu, Haiyang.,Jian, Minyu.,Liu, Shu.,Li, Ang.,Li, Shaowu.,...&Han, Ruquan.(2019).Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation.NEUROSCIENCE LETTERS,707,7.
MLA	Liu, Haiyang,et al."Preserved individual differences in functional connectivity patterns under dexmedetomidine-induced sedation".NEUROSCIENCE LETTERS 707(2019):7.