Cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia
	Zeng, F.1; Lan, L.1; Tang, Y.1; Liu, M.2; Liu, X.1; Song, W.3,4; Li, Y.1; Qin, W.5; Sun, J.5; Yu, S.1
刊名	NEUROGASTROENTEROLOGY AND MOTILITY
	2015-04-01
卷号	27 期号:4 页码:559-568
关键词	acupoint specificity cerebral activity functional dyspepsia
英文摘要	Background To investigate the similarities and differences in cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia (FD). Methods Twenty right-handed FD patients were enrolled and randomized divided into two groups. Each patient received 20 sessions' electroacupuncture treatment. The acupoints used in Group A were four acupoints on the Stomach Meridian, and the acupoints used in Group B were four acupoints on the Gallbladder Meridian. PET-CT scans were performed before and after acupuncture treatment to record the changes of cerebral glycometabolism. Key Results After treatment, the dyspepsia symptoms and the quality of life (QOL) of the patients in each group were significantly improved (p < 0.05) and there was insignificant difference in efficacy between the two groups (p > 0.05). In Group A, deactivation in brainstem, bilateral anterior cingulate cortex (ACC) and cerebellum, left superior medial frontal gyrus, orbital frontal cortex (OFC), and thalamus, etc., and activation in bilateral middle cingulate cortex (MCC), precuneus and lingual gyrus, etc. were observed. In Group B, deactivation in brainstem, bilateral thalamus, putamen, ACC, postterior cingulate cortex, hippocampus and cerebellum, etc., and activation in bilateral MCC, precuneus, left OFC, etc. were observed (p < 0.05, Family-wise error corrected). Conclusions & Inferences Different acupoints have similar clinical efficacy but relatively different cerebral responses. The influence on the sensory transduction regions (brainstem and thalamus) and visceral modulation regions might be the common mechanism of different acupoints treating for FD, and the modulation on some emotion/cognition-related areas (e.g., prefrontal cortex) is the potential difference between the different acupoints.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Gastroenterology & Hepatology ; Clinical Neurology ; Neurosciences
研究领域[WOS]	Gastroenterology & Hepatology ; Neurosciences & Neurology
关键词[WOS]	QUALITY-OF-LIFE ; ACUPUNCTURE TREATMENT ; PET-CT ; CONNECTIVITY ANALYSIS ; GASTRIC-MOTILITY ; BRAIN ACTIVITY ; SPECIFICITY ; DISORDERS ; ANXIETY ; DEPRESSION
收录类别	SCI
语种	英语
WOS记录号	WOS:000364740900012
公开日期	2016-02-26
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/10504]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Chengdu Univ Tradit Chinese Med, Acupunture & Tuina Sch, Teaching Hosp 3, Chengdu 610075, Sichuan, Peoples R China 2.Hunan Univ Tradit Chinese Med, Acupunture & Tuina Sch, Changsha, Hunan, Peoples R China 3.Sichuan Acad Med Sci, PET CT Ctr, Chengdu, Sichuan, Peoples R China 4.Sichuan Prov Peoples Hosp, Chengdu, Sichuan, Peoples R China 5.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian, Shaanxi, Peoples R China 6.Univ Penn, Dept Biol, Philadelphia, PA 19104 USA 7.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zeng, F.,Lan, L.,Tang, Y.,et al. Cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia[J]. NEUROGASTROENTEROLOGY AND MOTILITY,2015,27(4):559-568.
APA	Zeng, F..,Lan, L..,Tang, Y..,Liu, M..,Liu, X..,...&Liang, F..(2015).Cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia.NEUROGASTROENTEROLOGY AND MOTILITY,27(4),559-568.
MLA	Zeng, F.,et al."Cerebral responses to puncturing at different acupoints for treating meal-related functional dyspepsia".NEUROGASTROENTEROLOGY AND MOTILITY 27.4(2015):559-568.