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A deep learning method for repurposing antiviral drugs against new viruses via multi-view nonnegative matrix factorization and its application to SARS-CoV-2
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-16
作者:
Su, XR (Su, Xiaorui) [1]
;
Hu, L (Hu, Lun) [1]
;
You, ZH (You, Zhuhong) [2]
;
Hu, PW (Hu, Pengwei) [1]
;
Wang, L (Wang, Lei) [3]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/05/06
SARS-CoV-2
drugrepositioning
constrained multi-view nonnegative matrix factorization
deeplearning
graphconvolutionalnetwork
HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
Calibration of the air shower energy scale of the water and air Cherenkov techniques in the LHAASO experiment
期刊论文
PHYSICAL REVIEW D, 2021, 卷号: 104, 期号: 6
作者:
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, L. X.
;
Bai, Y. X.
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2021/10/08
Ultrahigh-energy photons up to 1.4 petaelectronvolts from 12 γ-ray Galactic sources
期刊论文
Nature, 2021, 卷号: 594, 期号: 7861, 页码: 33-36
作者:
Cao, Zhen
;
Aharonian, F. A.
;
An, Q.
;
Axikegu
;
Bai, L. X.
收藏
  |  
浏览/下载:156/0
  |  
提交时间:2021/07/17
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
An Efficient Computational Model for Large-Scale Prediction of Protein-Protein Interactions Based on Accurate and Scalable Graph Embedding
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 2, 页码: 1-10
作者:
Su, XR (Su, Xiao-Rui)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Hu, L (Hu, Lun)[ 1,2,3 ]
;
Huang, YA (Huang, Yu-An)[ 1 ]
;
Wang, Y (Wang, Yi)[ 1,2,3 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
large-scale
protein-protein interaction
GraphZoom
weighted graph
graph embedding
In silico drug repositioning using deep learning and comprehensive similarity measures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 增刊3, 页码: 1-14
作者:
Yi, HC (Yi, Hai-Cheng) 1 , 2
;
You, ZH (You, Zhu-Hong) 1
;
Wang, L (Wang, Lei) 1
;
Su, XR (Su, Xiao-Rui) 1 , 2
;
Zhou, X (Zhou, Xi) 1
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/07/14
Drug repositioningDrug-disease interactionGated recurrent unitsGaussian interaction profile kernelMachine learning
LDGRNMF: LncRNA-disease associations prediction based on graph regularized non-negative matrix factorization
期刊论文
NEUROCOMPUTING, 2021, 卷号: 424, 期号: 2, 页码: 236-245
作者:
Wang, MN (Wang, Mei-Neng)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/03/05
LncRNA-disease associations
LncRNA-disease similarity
Nonnegative matrix factorization
Graph regularization
MeSHHeading2vec: a new method for representing MeSH headings as vectors based on graph embedding algorithm
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 2, 页码: 2085-2095
作者:
Guo,ZH (Guo, Zhen-Hao) 1
;
You,ZH (You,Zhu-Hong) 1, 2
;
Huang,DS (Huang, De-Shuang) 3, 4
;
Yi, HC (Yi, Hai-Cheng) 2
;
Zheng, K (Zheng, Kai) 5
收藏
  |  
浏览/下载:111/0
  |  
提交时间:2021/08/09
MeSHHeading2vecMeSH relationship networkgraph embeddingcomputational prediction model
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
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