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科研机构
兰州大学 [41]
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期刊论文 [41]
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2016 [1]
2015 [1]
2014 [2]
2013 [2]
2012 [6]
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pharmacol... [41]
chemistry [17]
computer s... [8]
biochemist... [4]
immunology [1]
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Studies on the IC50 of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 1, 页码: 33-42
作者:
Yang, HZ
;
Liu, X
;
Ye, ZL
;
Song, FC
;
Cui, LH
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/11
Gene expression programming
IC50
kinase inhibitors
quantitative structure activity relationship
cell division cycle 7
trisubstituted thiazoles
Perspectives on Biologically Active Camptothecin Derivatives
期刊论文
MEDICINAL RESEARCH REVIEWS, 2015, 卷号: 35, 期号: 4, 页码: 753-789
作者:
Liu, YQ
;
Li, WQ
;
Morris-Natschke, SL
;
Qian, KD
;
Yang, L
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/11
camptothecins
DNA topoisomerase I
biological activities
structure-activity relationship
Synthesis and structure-activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 6
-
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  |  
浏览/下载:4/0
  |  
提交时间:2014/12/05
Aporphine alkaloids
Acetylcholinesterase inhibitors
Structure-activity relationships
Evaluation of insecticidal activity of camptothecin analogs against Brontispa longissima
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 2, 页码: 980-986
作者:
Yang, L
;
Zhang, ZJ
;
Liu, YQ
;
Zhao, CY
;
Wang, MJ
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  |  
浏览/下载:3/0
  |  
提交时间:2015/12/29
Camptothecin
Insecticidal activity
Brontispa longissima
Structure-activity relationships
Molecular design of new aggrecanases-2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 19
-
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  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Aggrecanase-2
Inhibitor
Molecular design
Quantitative structure-activity relationship
Molecular docking
Structure and antioxidant activity study of sulfated acetamido-polysaccharide from Radix Hedysari
期刊论文
FITOTERAPIA, 2013, 卷号: 89, 页码: 20-32
作者:
Dang, ZL
;
Feng, DM
;
Liu, XH
;
Yang, T
;
Guo, L
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  |  
浏览/下载:1/0
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提交时间:2015/12/29
Radix Hedysari
2D NMR
Structure
Polysaccharide
Atomic force microscopy
Electron microscopy
QSAR Studies of PTP1B Inhibitors: 1, 2-Naphthoquinone Derivatives
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2012, 卷号: 9, 期号: 10
-
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  |  
浏览/下载:2/0
  |  
提交时间:2014/12/05
Diabetes mellitus
Multiple linear regression (MLR)
1, 2-naphoquinone derivatives
Protein tyrosine phosphatase 1B (PTP1B)
Quantitative structure-activity relationships (QSAR)
Radial basis function neural networks (RBFNN)
Isolation, modification and cytotoxic evaluation of flavonoids from Rhododendron hainanense
期刊论文
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2012, 卷号: 64, 期号: 12, 页码: 1785-1792
作者:
Zhao, J
;
Ding, HX
;
Zhao, DG
;
Wang, CM
;
Gao, K
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  |  
浏览/下载:2/0
  |  
提交时间:2015/12/14
cytotoxicity
flavonoids
Rhododendron hainanense
structure-activity relationship
QSAR Studies of PTP1B Inhibitors: Recent Advances and Perspectives
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2012, 卷号: 19, 期号: 25
-
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2014/12/05
Diabetes mellitus
protein tyrosine phosphatase 1B inhibitors
type 2 diabetes
drug design
virtual screening
quantitative structure-activity relationships (QSAR)
3D-QSAR
comparative molecular field analysis (CoMFA)
comparative molecular similarity indices analysis (CoMSIA)
2D-QSAR
multiple linear regression (MLR)
radial basis function neural networks (RBFNN)
Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships
期刊论文
LIFE SCIENCES, 2012, 卷号: 90, 期号: 23-24
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Steroidal alkaloids
Holarrhena antidysenterica
Alzheimer's disease
Acetylcholinesterase inhibitor
Structure-activity relationships
Conessimin
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