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科研机构
上海药物研究所 [101]
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期刊论文 [100]
会议论文 [1]
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2021 [3]
2020 [6]
2019 [5]
2018 [7]
2017 [7]
2016 [7]
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Nitrogenous Sesquiterpenoids from the South China Sea Nudibranch Hexabranchus sanguineus and Its Possible Sponge-Prey Acanthella cavernosa: Chiral Separation, Stereochemistry and Chemical Ecology
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 2, 页码: 235-246
作者:
Shen, Shou-Mao
;
Zhang, Zai-Yong
;
Yao, Li-Gong
;
Wang, Jian-Rong
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
Hexabranchus sanguineus
Acanthella cavernosa
Chiral separation
Stereochemistry
Chemical ecology
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Ximaoglaucumins A-F, new cembranoids with anti-inflammatory activities from the South China Sea soft coral Sarcophyton glaucum
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 38, 页码: 10
作者:
Shen, Shou-Mao
;
Li, Wang-Sheng
;
Ding, Xun
;
Luo, Hui
;
Zhang, Hai-Yan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/08/17
Soft coral
Sarcophyton glaucum
Cembranoids
Anti-inflammation
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
期刊论文
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:
Zhuang, Youwen
;
Xu, Peiyu
;
Mao, Chunyou
;
Wang, Lei
;
Krumm, Brian
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  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Further new complex daphniphyllum alkaloids from the stems and leaves of Daphniphyllum calycinum: Structure and stereochemistry
期刊论文
TETRAHEDRON, 2020, 卷号: 76, 期号: 49, 页码: 8
作者:
Shen, Shou-Mao
;
Li, Heng
;
Wang, Jian-Rong
;
Zeng, Yan-Bo
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Daphniphyllum calycinum
Daphniphyllum alkaloids
Absolute configuration
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
期刊论文
CANCER CELL, 2020, 卷号: 38, 期号: 1, 页码: 79-+
作者:
Su, Rui
;
Dong, Lei
;
Li, Yangchan
;
Gao, Min
;
Han, Li
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  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells (vol 37, pg 1587, 2020)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 2
作者:
Wang, Yue-qin
;
Shen, Ai-jun
;
Sun, Jing-ya
;
Wang, Xin
;
Liu, Hong-chun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
KRAS
anticancer therapy
PDE delta
EPHA2
RAF
MEK
ERK signaling
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