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科研机构
上海药物研究所 [15]
内容类型
期刊论文 [15]
发表日期
2021 [2]
2020 [3]
2019 [2]
2018 [1]
2017 [2]
2016 [4]
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Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:
Wu, Qian
;
Chen, Dan-Qi
;
Sun, Lin
;
Huan, Xia-Juan
;
Bao, Xu-Bin
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2021/05/24
N2817
Bivalent BET inhibitors
Monovalent BET inhibitors
TAF1
Anticancer activity
An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy
期刊论文
NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 16
作者:
Wang, Cong
;
Sun, Wanbing
;
Zhang, Jun
;
Zhang, Jianping
;
Guo, Qinghua
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/21
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way
期刊论文
FASEB JOURNAL, 2020, 页码: 16
作者:
Wu, Yanwei
;
Wu, Bing
;
Zhang, Zongwang
;
Lu, Huimin
;
Fan, Chen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
IBD
M1
M2
ulcerative colitis
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:
Li, Heng
;
Fan, Chen
;
Feng, Chunlan
;
Wu, Yanwei
;
Lu, Huimin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
artemisininanaloguesm934amelioratesdssinducedmouseulcerativecolitisviasuppressingneutrophilsandmacrophages
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 10, 页码: 1633
作者:
Yan Yuxi
;
Shao Meijuan
;
Qi Qing
;
Xu Yansheng
;
Yang Xiaoqian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
NF-KAPPA-B
SODIUM-INDUCED COLITIS
MURINE COLITIS
MICE
CYTOKINES
CELLS
SM934
artemisinin analogue
ulcerative colitis
inflammatory bowel disease (IBD)
neutrophils macrophage
NF-kappa B
RAW 2647 cells
THP-1-derived macrophages
Acidity-Triggered Ligand-Presenting Nanoparticles To Overcome Sequential Drug Delivery Barriers to Tumors
期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 9, 页码: 5429-5436
作者:
Wang, Tingting
;
Wang, Dangge
;
Liu, Jianping
;
Feng, Bing
;
Zhou, Fangyuan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Drug delivery barriers
acid-responsive
ligand presentation
tumor microenvironment
cancer therapy
High-Throughput Study of the Effects of Celastrol on Activated Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis
期刊论文
GENES, 2017, 卷号: 8, 期号: 9
作者:
Fang, Zhengyu
;
He, Dongyi
;
Yu, Bo
;
Liu, Feng
;
Zuo, Jianping
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
celastrol
rheumatoid arthritis
fibroblast-like synoviocyte
chemokine
NF-B signaling pathway
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