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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载:137/0  |  提交时间:2019/06/28
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:  Xiamuxi, H (Xiamuxi, Hainimu);  Wang, Z (Wang, Zhen);  Li, JF (Li, Jianfeng);  Wang, Y (Wang, Yu);  Wu, CH (Wu, Chunhui)
收藏  |  浏览/下载:111/0  |  提交时间:2017/10/31


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