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科研机构
上海药物研究所 [7]
合肥物质科学研究院 [6]
昆明植物研究所 [1]
海洋研究所 [1]
内容类型
期刊论文 [15]
发表日期
2020 [15]
学科主题
Biochemist... [1]
Biophysics [1]
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DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Immune microenvironment features and efficacy of PD-1/PD-L1 blockade in non-small cell lung cancer patients with EGFR or HER2 exon 20 insertions
期刊论文
THORACIC CANCER, 2020
作者:
Chen, Kaiyan
;
Pan, Guoqiang
;
Cheng, Guoping
;
Zhang, Fanrong
;
Xu, Yanjun
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/28
EGFR
HER2
immunotherapy
NSCLC
PD‐
L1
Efficacy of Pyrotinib in HER2-Overexpressing Salivary Duct Carcinoma With Lung Metastasis: A Case Report
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Yang, Zi-yan
;
Huang, Jia-huan
;
Chen, Bo
;
Xu, Chun-wei
;
Lei, Lei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/11/30
salivary duct carcinoma
tyrosine kinase inhibitor
pyrotinib
HER2 positive
targeted
Structurally diverse halosesquiterpenoids from the red alga Laurencia composita Yamada
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Hu, Zhi-Biao
;
Yu, Xiao-Qing
;
Wang, Bin
;
Liu, Ai-Hong
;
Zhao, Tian-Sheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/24
Laurencia composita
Chamigrane sesquiterpenoids
Bisabolane sesquiterpenoids
Nerolidol derivative
Modified Mosher's method
Antifungal activity
Antibacterial activity
Repurposing of Kinase Inhibitors for Treatment of COVID-19
期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:
Weisberg, Ellen
;
Parent, Alexander
;
Yang, Priscilla L.
;
Sattler, Martin
;
Liu, Qingsong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/10/26
Coronavirus
SARS-CoV-2
SARS-CoV
MERS-CoV
kinase inhibitors
pharmacokinetics
antiviral therapy
COVID-19
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
PD-L1 expression and T cells infiltration in patients with uncommon EGFR-mutant non-small cell lung cancer and the response to immunotherapy
期刊论文
LUNG CANCER, 2020, 卷号: 142
作者:
Chen, Kaiyan
;
Cheng, Guoping
;
Zhang, Fanrong
;
Zhu, Guanxia
;
Xu, Yanjun
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/26
Uncommon EGFR
Non-small cell lung cancer
PD-L1
T cell
Immunotherapy
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
期刊论文
ONCOGENE, 2020, 卷号: 39
作者:
Jin, Ying
;
Bao, Hua
;
Le, Xiuning
;
Fan, Xiaojun
;
Tang, Ming
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
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