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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:  Wu, Xu;  Yin, Chun;  Ma, Jiang;  Chai, Stella;  Zhang, Chunyuan
收藏  |  浏览/下载:38/0  |  提交时间:2021/11/04
Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8644-8665
作者:  Kong, Qidi;  Pan, Wei;  Xu, Heng;  Xue, Yaru;  Guo, Bin
收藏  |  浏览/下载:37/0  |  提交时间:2021/08/17
Dihydro-beta-agarofuran-Type Sesquiterpenoids from the Seeds of Celastrus virens and Their Multidrug Resistance Reversal Activity against the KB/VCR Cell Line 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 3, 页码: 588-600
作者:  Mu, Hongyan;  Tang, Shuai;  Zuo, Quan;  Huang, Min;  Zhao, Weimin
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 10
作者:  Song, Runzhe;  Wang, Yue;  Wang, Minghui;  Gao, Ruixuan;  Yang, Teng
收藏  |  浏览/下载:20/0  |  提交时间:2020/12/24
Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992
作者:  Song, Bichao;  Xie, Peipei;  Li, Yingzi;  Hao, Jiping;  Wang, Lu
收藏  |  浏览/下载:21/0  |  提交时间:2020/12/24
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 8
作者:  Chen, Lu;  Quan, Haitian;  Xu, Zhongliang;  Wang, Hao;  Xia, Yuanzhi
收藏  |  浏览/下载:17/0  |  提交时间:2020/12/24
Discovery of synergistic activity of fluoroquinolones in combination with antimicrobial peptides against clinical polymyxin-resistant Pseudomonas aeruginosa DK2 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 2, 页码: 413-417
作者:  Zheng, Xinyu;  Cao, Qiao;  Cao, Qin;  Mao, Fei;  Li, Xiaokang
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01
leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:  Liao Xiaoying;  Deng Qiangqiang;  Han Li;  Wu Zhitao;  Peng Zhaoliang
收藏  |  浏览/下载:83/0  |  提交时间:2020/07/01
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:  Liao, Xiao-ying;  Deng, Qiang-qiang;  Han, Li;  Wu, Zhi-tao;  Peng, Zhao-liang
收藏  |  浏览/下载:54/0  |  提交时间:2020/07/01
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:  Xie, Cen;  Takahashi, Shogo;  Brocker, Chad N.;  He, Shijun;  Chen, Li
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01


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