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科研机构
上海药物研究所 [13]
合肥物质科学研究院 [4]
长春光学精密机械与物... [1]
内容类型
期刊论文 [18]
发表日期
2020 [18]
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Mutagenicity of 7-ketocholesterol in CHO cells: The role of lipid peroxidation
期刊论文
TOXICOLOGY, 2020, 卷号: 446
作者:
Wang, Xiaofei
;
Li, Yintao
;
Xia, Xuanyi
;
Zhang, Min
;
Ge, Chunmei
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/12/28
7-ketocholesterol
Mutagenicity
DNA damage
Apoptosis
Lipid peroxidation
Combinations of proteasome inhibitors with obatoclax are effective for small cell lung cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Yin, Yan-ping
;
Shi, Wen-hao
;
Deng, Ke
;
Liu, Xiao-li
;
Li, Hong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/28
small cell lung cancer
obatoclax
bortezomib
carfilzomib
MCL-1
apoptosis
FOXM1
proteomics analysis
Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56
作者:
Xu, Xiaoju
;
Xu, Xu
;
Hao, Yanping
;
Zhu, Xialin
;
Lu, Jian
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21
作者:
Gao, Yang
;
Wen, Pengbo
;
Chen, Bin
;
Hu, Guanshuo
;
Wu, Lijun
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  |  
浏览/下载:49/0
  |  
提交时间:2020/11/30
CDC20
radiotherapy
Mcl-1
p-Chk1
mitochondrial-dependent apoptotic pathway
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
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  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 195
作者:
Wang, Xiaofei
;
Li, Yintao
;
Xiao, Hourong
;
Zhang, Min
;
Bao, Teng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/11/26
Microcystin-LR
DNA damage
Peroxynitrite
Mitochondria
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
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