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上海药物研究所 [10]
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期刊论文 [46]
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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer
期刊论文
BIOMATERIALS, 2021, 卷号: 278
作者:
Wang, Liying
;
Liu, Zimo
;
Zhou, Quan
;
Gu, Sufang
;
Liu, Xiangsheng
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/11/29
Pancreatic cancer
Polymeric prodrug
Calcipotriol
Cancer-associated fibroblast
Metastasis
Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:
Ji, Zhaodong
;
Tian, Wenjuan
;
Gao, Wen
;
Zang, Rongyu
;
Wang, Huaying
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  |  
浏览/下载:30/0
  |  
提交时间:2021/08/30
IL-8
tumor stemness
epithelial ovarian cancer
cancer-associated ovarian fibroblasts
Notch3 signal pathway
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
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  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Cancer-associated fibroblast-derived exosomal miR-382-5p promotes the migration and invasion of oral squamous cell carcinoma
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 42, 期号: 4, 页码: 1319-1328
作者:
Sun, Li-Ping
;
Xu, Kai
;
Cui, Jing
;
Yuan, Dao-Ying
;
Zou, Bo
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/11
oral squamous cell carcinoma
cancer-associated fibroblasts
miR-382-5p
exosome
migration
invasion
Upregulation of Fibroblast Growth Factor 19 Is Associated with the Initiation of Colorectal Adenoma
期刊论文
DIGESTIVE DISEASES, 2019, 卷号: 37, 期号: 3, 页码: 214-225
作者:
Wang, Dongyang
;
Zhang, Jianjun
;
Li, Zengjun
;
Han, Jianjun
;
Gao, Yongsheng
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Colorectal adenoma
Colorectal cancer
Fibroblast growth factor 19
Fibroblast growth factor receptor 4
Biological marker
c11anovelfibroblastgrowthfactorreceptor1fgfr1inhibitorsuppressesbreastcancermetastasisandangiogenesis
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 6, 页码: 823
作者:
Chen Zhuo
;
Tong Linjiang
;
Tang Baiyou
;
Liu Hongyan
;
Wang Xin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
SELECTIVE INHIBITOR
THERAPEUTIC TARGET
DISCOVERY
ACTIVATION
EXPRESSION
PATHWAY
POTENT
C11
FGFR1 inhibitor
antitumor
breast cancer
metastasis
angiogenesis
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Chen, Zhuo
;
Tong, Lin-Jiang
;
Tang, Bai-You
;
Liu, Hong-Yan
;
Wang, Xin
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice
期刊论文
STEM CELLS, 2018, 卷号: 36, 期号: 8, 页码: 1273-1285
作者:
Lu, Hui
;
Cheng, Gang
;
Hong, Feng
;
Zhang, Lei
;
Hu, Youhong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Neural stem cells
Notch signaling pathway
Hes5
Adult hippocampal neurogenesis
Learning and memory
2-phenylamino-quinazoline
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