中国开放科研知识云: 检索

Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018, 卷号: 1863, 期号: 8, 页码: 806-822
作者: Zhao, Zhen-Wang; Zhang, Min; Chen, Ling-Yan; Cong, Duo; Xia, Xiao-Dan

收藏 | 浏览/下载：4/0 | 提交时间：2019/12/27

HSP70 heat shock protein 70 ABCA1 ATP binding cassette transporter A1 ABCG1 ATP binding cassette transporter G1 RCT reverse cholesterol transport HDL high density lipoprotein JNK c-Jun N-terminal kinase MAPK mitogen-activated protein kinase NF-κB nuclear factor-kappa B TLR toll-like receptor ELK-1 ETS transcription factor HSP70 Atherosclerosis Cholesterol efflux ABCA1 ABCG1 Reverse cholesterol transport

Transient receptor potential vanilloid-type 2 targeting on stemness in liver cancer 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 105, 页码: 697-706
作者: Hu, Zecheng; Cao, Xiaocheng; Fang, Yu; Liu, Guoxing; Xie, Chengzhi

收藏 | 浏览/下载：27/0 | 提交时间：2019/12/27

HHC Human Hepatocellular Carcinoma LCSLC sliver cancer stem-like cells TRPV2 Transient Receptor Potential Vanilloid-type 2 channel TRP Transient Receptor Potential SCID severe combined immunodeficiency ALDH1 aldehyde dehydrogenase 1 GFP green fluorescent protein LPL lysophospholipids CAPE caffeic acid phenethyl ester hrbFGF human recombinant basic ﬁbroblast growth factor hrEGF human recombinant epidermal growth factor TRPC Transient Receptor Potential Canonical TRPM Transient Receptor Potential Melastatin TRPV Transient Receptor Potential Vanilloid JNK1 c-jun N-terminal kinase-1 MRP multidrug-resistant protein ABCC2 ATP-binding cassette subfamily C member 2 MRP4 Multidrug Resistance Protein 4 CSC Cancer Stem Cell DMEM Dulbecco modified Eagle medium Liver cancer Liver cancer stem cell Transient receptor potential vanilloid-type 2 channel Probenecid Tranilast Self-renewal

Steroid receptor RNA activator: Biologic function and role in disease 期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者: Liu, Chan; Wu, Hong-Tao; Zhu, Neng; Shi, Ya-Ning; Liu, Zheng

收藏 | 浏览/下载：61/0 | 提交时间：2019/12/27

AF-2 activation function-2 AR androgen receptor C/EBPα ccaat-enhancer-binding protein α CTCF CCCTC-binding factor Ddx5 DEAD box protein 5 ERα estrogen receptor α GR glucocorticoid receptor Hes1 hairy and enhancer of split-1 HP1γ heterochromatin protein 1γ JNK c-Jun N-terminal kinases lncRNA long noncoding RNA MyoD myogenic differentiation 1 NANOG homeobox protein NANOG NR nuclear receptor(s) p38 MAPK mitogen-activated protein kinase PACT protein kinase RNA activator PCOS polycystic ovary syndrome PKR protein kinase RNA-dependent PPARγ Peroxisome Proliferator-Activated Receptor gamma PR progesterone receptor PRC2 polycomb repressive complex 2 preTCRα pre T-cell antigen receptor alpha Pus1p pseudouridine synthesis protein RAR retinoic acid receptor RBP-J recombination signal-binding protein J RRM RNA recognition motif SF-1 steroidogenic factor 1 SHARP retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein SLIRP stem-loop loop-interacting RNA RNA-binding protein SRA Steroid receptor RNA activator SRAP steroid receptor RNA activator protein SRC-1 steroid receptor coactivator-1 STR stem-loop structure TNFα tumor necrosis factor α TRBP transactivation response RNA-binding protein TrxG trithorax group SRA Long noncoding RNAs Nuclear receptor Transcriptional coactivator

Autophagy: A double-edged sword in intervertebral disk degeneration 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2016, 卷号: 457, 页码: 27-35
作者: Zhang, Shu-Jun; Yang, Wei; Wang, Cheng; He, Wen-Si; Deng, Hai-Yang

收藏 | 浏览/下载：15/0 | 提交时间：2019/12/27

IVD intervertebral disk NP nucleus pulposus AF annulus fibrosus CEPs cartilaginous endplates ECM extracellular matrix Col II type II collagen Col I type I collagen IDD intervertebral disk degeneration LBP low back pain miRNAs microRNAs ADAMTS a disintegrin and metalloprotease with thrombospondin motif MMP matrix metalloproteinases HSC70 heat shock cognate protein of 70 kDa LAMP2A lysosome-associated membrane protein type-2 A Atg autophagy-related genes ULK uncoordinated-51-like kinase PI3KCIII class III phosphatidylinositol 3-kinase mTORC1 mammalian target of rapamycin complex 1 DFCP1 double FYVE-containing protein 1 3-MA 3-methyladenine LC3 microtubule-associated protein 1 light chain 3 PE phosphatidyl ethanolamine LAMP-2 lysosomal membrane protein 2 TNF-α tumor necrosis factor-α IL-1β interleukin-1β NF-κB nuclear factor-κB JNK c-Jun N-terminal kinase SIRT1 silent mating type information regulator 2 homolog 1 TGF-β1 transforming growth factor-β1 ERK1/2 extracellular signal-regulated kinase 1/2 GRP78 glucose regulated protein 78 H2O2 hydrogen peroxide Autophagy IVD IDD NP AF

Interleukin-1β in intervertebral disk degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者: Yang, Wei; Yu, Xiao-Hua; Wang, Cheng; He, Wen-Si; Zhang, Shu-Jun

收藏 | 浏览/下载：12/0 | 提交时间：2019/12/27

IDD intervertebral disk degeneration IL-1 interleukin-1 IVD intervertebral disk ECM extracellular matrix LBP low back pain MMPs matrix metalloproteinases NP nucleus pulposus AF annulus fibrosus Col II type II collagen Col I type I collagen NTP N-terminal peptide NLS nuclear localization sequence IL-1RII IL-1 receptor type II TLRs Toll-like receptors IL-1RI IL-1 receptor type I IL-1RAcP IL-1 receptor accessory protein TIR Toll-like/IL-1 receptor MyD88 myeloid differentiation factor 88 TNF tumor necrosis factor NF-κB nuclear factor-kappa B MAPK mitogen-activated protein kinase IL-1Ra IL-1 receptor antagonist IFN-γ interferon-γ CCL CC chemokine ligand CXCL CX chemokine ligand ADAMTSs a disintegrin and metalloprotease with thrombospondin motifs TIMPs tissues inhibitors of metalloproteinases VEGF vascular endothelial growth factor NGF nerve growth factor BDNF brain-derived neurotrophic factor ROS reactive oxygen species SOD superoxide dismutase CAT catalase miRNAs microRNAs MSCs mesenchymal stem cells PRP platelet-rich plasma IL-1 IDD Inflammatory responses Angiogenesis Apoptosis

The protective functions of omentin in cardiovascular diseases 期刊论文
Clinica Chimica Acta, 2015, 卷号: 448, 页码: 98-106
作者: Tan, Yu-Lin; Zheng, Xi-Long; Tang, Chao-Ke*

收藏 | 浏览/下载：7/0 | 提交时间：2019/12/27

CVD cardiovascular disease CAD coronary heart disease PAH pulmonary arterial hypertension MIRI myocardial ischemia–reperfusion injury TGF-β transforming growth factor-β ICAM-1 intercellular adhesion molecule-1 VCAM-1 vascular cell adhesion molecule-1 MCP-1 monocyte chemoattractant protein-1 PI3K phosphatidylinositol 3-kinase AKT protein kinase B AMPK AMP-activated protein kinase TNF-α tumor necrosis factor-α JNK c-Jun N-terminal kinase VSMC vascular smooth muscle cell COX-2 cyclooxygenase-2 PDGF-BB platelet-derived growth factor-BB NO nitric oxide BNP brain natriuretic peptide MetS metabolic syndrome SCF slow coronary flow phenomenon LV left ventricular AMI acute myocardial infarction THRT thyroid hormone replacement therapy c-IMT carotid intima-media thickness DM diabetes mellitus IBD inflammatory bowel disease CD Crohn's disease Omentin Protective functions Cardiovascular diseases

Apelin and its receptor APJ in cardiovascular diseases 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2014, 卷号: 428, 页码: 1-8
作者: Yu, Xiao-Hua*; Tang, Zhi-Bin; Liu, Li-Jing; Qian, Hong; Tang, Shi-Lin

收藏 | 浏览/下载：8/0 | 提交时间：2019/12/27

ABCA1 ACAT1 APJ ATP-binding cassette transporter A1 Ang II Ang-1 Apelin Atherosclerosis BMP BNP CAD COX-2 FGF2 GSK HDAC HIF-1alpha Heart failure Hypertension ICAM-1 IRS1 JNK MCP-1 MEF2 MIRI NO PAH PDGF-BB PGE2 PI3K PKB PKC PPAR response elements PPREs TGF-beta TNF-alpha VCAM-1 VEGFA VSMC acyl coenzyme A:cholesterol acyltransferase-1 angiopoietin-1 angiotensin II apo E apolipoprotein E bone morphogenic protein brain natriuretic peptide c-Jun N-terminal kinase coronary heart disease cyclooxygenase-2 fibroblast growth factor 2 glycogen synthase kinase histone deacetylase hypoxia-inducible factor 1alpha insulin receptor substrate 1 intercellular adhesion molecule-1 monocyte chemoattractant protein-1 myocardial ischemia-reperfusion injury myocyte enhancer factor 2 nitric oxide phosphatidylinositol 3-kinase platelet-derived growth factor-BB prostaglandin E2 protein kinase B protein kinase C pulmonary arterial hypertension transforming growth factor-beta tumor necrosis factor-alpha vascular cell adhesion molecule-1 vascular endothelial growth factor type A vascular smooth muscle cell

Hydrogen sulfide as a potent cardiovascular protective agent 期刊论文
Clinica Chimica Acta, 2014, 卷号: 437, 页码: 78-87
作者: Yu, Xiao-Hua; Cui, Li-Bao; Wu, Kai; Zheng, Xi-Long; Cayabyab, Francisco S

收藏 | 浏览/下载：16/0 | 提交时间：2019/12/27

H2S hydrogen sulfide NO nitric oxide CO carbon monoxide CHD coronary heart disease PAH pulmonary arterial hypertension I/R ischemia/reperfusion CSE cystathionine-γ-lyase CBS cystathionine-ß-synthase 3-MST 3-mercaptopyruvate sulfurtransferase CAT cysteine aminotransferase KATP ATP-sensitive potassium SUR1 sulfonylurea receptor 1 VSMCs vascular smooth muscle cells PI3K phosphatidylinositol 3-kinase VEGF vascular endothelial growth factor ERK1/2 extracellular signal-regulated kinase 1/2 NF-κB nuclear factor-κB HIF-1α hypoxia-inducible factor 1α PIP3 phosphatidylinositol-3,4,5-trisphosphate ROS reactive oxygen species redox reduction/oxidation Nrf2 nuclear factor erythroid 2-related factor 2 JNK c-Jun N-terminal kinase oxLDL oxidized low-density lipoprotein PAG dl-propargylglycine dl Ang II angiotensin II HO-1 heme oxygenase-1 DATS diallyl trisulfide H2S CSE Atherosclerosis CHD Heart failure

Interleukin-17A in lipid metabolism and atherosclerosis 期刊论文
Clinica Chimica Acta, 2014, 卷号: 431, 页码: 33-39
作者: Yu, Xiao-Hua; Jiang, Na; Zheng, Xi-Long; Cayabyab, Francisco S; Tang, Zhi-Bin*

收藏 | 浏览/下载：3/0 | 提交时间：2019/12/27

IL-17 interleukin-17 Th17 T helper 17 IL-17R IL-17 receptor STAT3 signal transducer and activator of transcription 3 RORγ retinoic acid receptor-related orphan receptor γ IRF4 interferon regulatory factor 4 ERK extracellular signal-regulated kinase Ets1 E26 transformation-specific 1 15(S)-HETE 15(S)-hydroxyeicosatetraenoic acid SF1 alternative splicing factor MAPK mitogen-activated protein kinase PPARγ peroxisome proliferator-activated receptor γ TRAF tumor necrosis factor receptor-associated factor TAK1 transforming growth factor-β-activated kinase 1 TAB TAK1-binding protein IKK IκB kinase NF-κB nuclear factor kappa-B IKKi inducible IKK JNK c-Jun N-terminal kinase C/EBP CCAAT/enhancer-binding protein AP1 activator protein 1 USP ubiquitin-specific protease CXCL CXC chemokine ligand ASF alternative splicing factor Hsp90 heat shock protein 90 RCT reverse cholesterol transport ABCA1 ATP-binding cassette transporter A1 apo E apolipoprotein E LDLR low-density lipoprotein receptor FABP4 fatty acid-binding protein-4 IL-17A IL-17RA IL-17RC Lipid metabolism Atherosclerosis

Induction of apoptosis by casticin in cervical cancer cells: reactive oxygen species-dependent sustained activation of Jun N-terminal kinase 期刊论文
Acta Biochimica et Biophysica Sinica, 2012, 卷号: 44, 期号: 5, 页码: 442-449
作者: Zeng Fanxiang; Tian Li; Liu Fei; Cao Jianguo; Quan Meifang

收藏 | 浏览/下载：4/0 | 提交时间：2019/12/27

human cervical cancer casticin apoptosis reactive oxygen species c-Jun N-terminal kinase

在结果中检索

相关链接

CORC

联系我们