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科研机构
复旦大学上海医学院 [31]
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期刊论文 [30]
会议论文 [1]
发表日期
2019 [2]
2018 [2]
2017 [1]
2016 [3]
2015 [2]
2014 [4]
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专题:复旦大学上海医学院
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Design and Synthesis of the Diazirine-based Clickable Photo-Affinity Probe Targeting Sphingomyelin Synthase 2
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 6
作者:
Wang, Penghui
;
Li, Zhining
;
Jiang, Lulu
;
Zhou, Lu
;
Ye, Deyong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
sphingomyelin
photo-affinity labeling
diazirine
phosphatidylcholine
phosphoethanolamine
Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163
作者:
Li, Yali
;
Huang, Taomin
;
Lou, Bin
;
Ye, Deyong
;
Qi, Xiangyu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
Inhibitor
ApoE KO mice
Atherosclerosis
Discovery of 4-Benzyloxybenzo[d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/db Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18
作者:
Mo, Mingguang
;
Yang, Jintong
;
Jiang, Xian-Cheng
;
Cao, Yu
;
Fei, Jinyu
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 47
作者:
Lou, Bin
;
Liu, Qi
;
Hou, Jiahui
;
Kabir, Inamul
;
Liu, Peipei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
sphingolipid
phospholipid
lipid
lipid metabolism
cancer
2-hydroxy-oleic acid (2OHOA)
anti-cancer drug
lysophosphatidylcholine acyltransferase (LPCAT)
sphingomyelin synthase (SMS)
sphingomyelin
phosphatidylcholine
Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15
作者:
Qi, Xiang-Yu
;
Cao, Yang
;
Li, Ya-Li
;
Mo, Ming-Guang
;
Zhou, Lu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
Anti-atherosclerosis
Oxazolopyridine
Selective inhibitor
SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells
期刊论文
CELL BIOLOGY AND TOXICOLOGY, 2016, 卷号: 32, 期号: 6
作者:
Jin, Guiying
;
Li, Yang
;
Zhu, Yuwen
;
Du, Lisha
;
Yan, Junkai
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase
P-glycoprotein
Multidrug resistance protein 2
Pregnane X receptor
Phosphorylated signal pathways
Chinese hamster ovary-sphingomyelin synthase2 biospecific extraction and liquid chromatography with tandem mass spectrometry analysis for the prediction of bioactive components of Rhizoma Polygoni Cuspidati
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2016, 卷号: 39, 期号: 6
作者:
Dong, Jibin
;
Liang, Jianying
;
Xue, Ying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Bioactive candidates
Biospecific extraction
Rhizoma Polygoni Cuspidati
Screening
Traditional Chinese medicine
Novel Dual Inhibitors of Secretory Phospholipase A(2) and Sphingomyelin Synthase: Design, Synthesis and Evaluation
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 10
作者:
Gong, Haojun
;
Zhou, Lu
;
Ye, Deyong
;
Gao, Xing
;
Li, Yali
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/06
Atherosclerosis
secretory phospholipase A(2) (sPLA(2))
sphingomyelin synthase (SMS)
dual inhibitors
Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 18
作者:
Li, Ya-li
;
Qi, Xiang-yu
;
Jiang, Hui
;
Deng, Xiao-dong
;
Dong, Yan-ping
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/19
Sphingomyelin synthase
Inhibitor
Structure-based virtual screening
Molecular docking
Point mutagenesis
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity
期刊论文
JOURNAL OF LIPID RESEARCH, 2015, 卷号: 56, 期号: 3
作者:
Ding, Tingbo
;
Kabir, Inamul
;
Li, Yue
;
Lou, Caixia
;
Yazdanyar, Amirfarbod
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/19
sphingomyelin synthase-related protein
sphingomyelin synthase 1
sphingomyelin synthase 2
mouse gene knockout
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