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Enhanced interaction between SEC2 mutant and TCR V induces MHC II-independent activation of T cells via PKC/NF-B and IL-2R/STAT5 signaling pathways
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 51, 页码: 19771-19784
作者:
Fu, Xuanhe
;
Xu, Mingkai
;
Song, Yubo
;
Li, Yongqiang
;
Zhang, Huiwen
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/06/04
interleukin
NF-B (NF-KB)
STAT transcription factor
signaling
signal transduction
IL-2
staphylococcal enterotoxin C2
superantigen
T-cell receptor
T-cell activation
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
作者:
Li, Zhengjun
;
Wei, Jiangxue
;
Yang, Yanli
;
Liu, Lili
;
Ma, Guanghui
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  |  
浏览/下载:260/0
  |  
提交时间:2019/04/03
Hepatitis b Core Protein
Thermal Stability
Particles
Purification
Host Cell Protein
Chromatography
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness
期刊论文
Developmental cell, 2018
作者:
Wang, Xinbo
;
Jin, Jiali
;
Wan, Fangning
;
Zhao, Linlin
;
Chu, Hongshang
收藏
  |  
浏览/下载:180/0
  |  
提交时间:2019/01/08
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography
期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
作者:
Li, Zhengjun
;
Wei, Jiangxue
;
Yang, Yanli
;
Ma, Xiaowei
;
Hou, Baidong
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  |  
浏览/下载:111/0
  |  
提交时间:2018/12/28
Hbc-vlp
Hydrophobic Interaction Chromatography
Surface Hydrophobicity Properties
Rational Design
Vaccine Candidates
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction
期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:
Chen, Danqi
;
Chen, Yuehong
;
Lian, Fulin
;
Chen, Liu
;
Li, Yanlian
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  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
Self-assembly of antigen proteins into nanowires greatly enhances the binding affinity for high-efficiency target capture
期刊论文
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 48, 页码: 41019-41025
作者:
Men, Dong
;
Zhou, Juan
;
Li, Wei
;
Wei, Cui-Hua
;
Chen, Yuan-Yuan
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  |  
浏览/下载:73/0
  |  
提交时间:2019/05/08
Self-assembly
Protein nanowire
Polyvalent interaction
Binding affinity
Sensitive immunoassay
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
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  |  
浏览/下载:54/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Global profiling of pkng interactions using a human proteome microarray reveals novel connections with cypa
期刊论文
Proteomics, 2018, 卷号: 18, 期号: 23, 页码: 13
作者:
Wu, Fan-Lin
;
Liu, Yin
;
Zhang, Hai-Nan
;
Jiang, He-Wei
;
Cheng, Li
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  |  
浏览/下载:74/0
  |  
提交时间:2019/05/08
Pkng
Huprot array
Cypa
Nf-kappa b
Erk1/2
Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 23, 页码: 12
作者:
Tang, Qiyi
;
Luo, Min-Hua
;
Reeves, Inez
;
Ahn, Jin-Hyun
;
Wen, Fayuan
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  |  
浏览/下载:59/0
  |  
提交时间:2018/12/29
cytomegalovirus (CMV)
immediate-early protein 1 (IE1)
herpes simplex virus (HSV)
infected cellular protein (ICP0)
promyelocytic leukemia protein (PML)
nuclear domain 10 (ND10)
SUMOylation
HSV-1
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
Naunyn-schmiedebergs archives of pharmacology, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
;
Qu, Lala
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/05/08
Beta(2)-adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
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