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Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:  Han, Haozhen;  Li, Chunpu;  Li, Man;  Yang, Lisheng;  Zhao, Sen
收藏  |  浏览/下载:36/0  |  提交时间:2020/12/24
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tao, Ling-xue;  Ji, Sha-sha;  Szaloki, Dora;  Kovacs, Tibor;  Mandi, Attila
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:  Xu, Ming-ming;  Ryan, Philip;  Rudrawar, Santosh;  Quinn, Ronald J.;  Zhang, Hai-yan
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:  Xu Mingming;  Ryan Philip;  Rudrawar Santosh;  Quinn Ronald J;  Zhang Haiyan
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:  Wang, Zhenkang;  Ma, Chunhua;  Wang, Yujie;  Xiao, Qiang;  Xu, Chenghui
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Neuroprotective Effect of Natural Alkaloid Fangchinoline Against Oxidative Glutamate Toxicity: Involvement of Keap1-Nrf2 Axis Regulation 期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1177-1186
作者:  Bao, Fengxia;  Tao, Lingxue;  Zhang, Haiyan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression 期刊论文
CELL RESEARCH, 2019, 卷号: 29, 期号: 10, 页码: 787-803
作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng;  Zhang, Jing;  Huang, Xun
收藏  |  浏览/下载:69/0  |  提交时间:2020/07/01
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:  Liu, Xia;  Wang, Wei;  Chen, Hua-li;  Zhang, Hai-yan;  Zhang, Nai-xia
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
作者:  Hao, Zongbing;  Liu, Liu;  Tao, Zhouteng;  Wang, Rui;  Ren, Haigang
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 6, 页码: 2654-2665
作者:  Chen, Xiangling;  Lu, Dayun;  Gao, Jing;  Zhu, Hongwen;  Zhou, Yanting
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01


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