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期刊论文 [116]
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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
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浏览/下载:8/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Hepatoprotective Effect of Oyster Peptide on Alcohol-Induced Liver Disease in Mice
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 15, 页码: 15
作者:
Wang, Xueqin
;
Yu, Huahua
;
Xing, Ronge
;
Li, Pengcheng
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  |  
浏览/下载:14/0
  |  
提交时间:2022/12/09
oyster peptide
alcohol-induced liver diseases
hepatoprotective effect
oxidative stress
inflammatory response
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
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  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+
作者:
Pan, Qiang
;
Zhong, Shanshan
;
Wang, Hanling
;
Wang, Xuege
;
Li, Ni
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  |  
浏览/下载:74/0
  |  
提交时间:2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
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  |  
浏览/下载:73/0
  |  
提交时间:2021/08/17
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
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  |  
浏览/下载:102/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
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  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Zika virus infection induces rnai-mediated antiviral immunity in human neural progenitors and brain organoids
期刊论文
Cell research, 2019, 卷号: 29, 期号: 4, 页码: 265-273
作者:
Xu, Yan-Peng
;
Qiu, Yang
;
Zhang, Boya
;
Chen, Guilai
;
Chen, Qi
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  |  
浏览/下载:540/0
  |  
提交时间:2019/05/08
Xinjiang herbal tea exerts immunomodulatory activity via TLR2/4-mediated MAPK signaling pathways in RAW264.7 cells and prevents cyclophosphamide-induced immunosuppression in mice
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 228, 页码: 179-187
作者:
Bai, Yujia
;
Jiang, Yunyao
;
Liu, Tingwu
;
Li, Fu
;
Zhang, Jianmei
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  |  
浏览/下载:35/0
  |  
提交时间:2021/11/10
Xinjiang herbal tea
Immunomodulatory effect
Toll-like receptor
Nuclear factor-kappa B
GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Zhou, Dongsheng
;
Lv, Dan
;
Wang, Zhen
;
Zhang, Yanhua
;
Chen, Zhongming
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  |  
浏览/下载:74/0
  |  
提交时间:2019/01/08
GLYX-13
disrupted-in-schizophrenia 1
N-methyl-D-aspartate receptor
N-methyl D-aspartate receptor subtype 2B
schizophrenia
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