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科研机构
湖南大学 [896]
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期刊论文 [859]
会议论文 [37]
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2019 [363]
2018 [219]
2017 [67]
2016 [54]
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Molecular Network-Based Drug Prediction in Thyroid Cancer.
期刊论文
International Journal of Molecular Sciences, 2019, 卷号: Vol.20 No.2, 页码: 263
作者:
Xu, Xingyu
;
Long, Haixia
;
Xi, Baohang
;
Ji, Binbin
;
Li, Zejun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/13
co-expression network
differential co-expression
differential gene
drug redirection
gene perturbation
thyroid cancer
Molecular Network-Based Drug Prediction in Thyroid Cancer.
期刊论文
International Journal of Molecular Sciences, 2019, 卷号: Vol.20 No.2, 页码: 263
作者:
Xu, Xingyu
;
Long, Haixia
;
Xi, Baohang
;
Ji, Binbin
;
Li, Zejun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/13
New windows into the brain: Central nervous system-derived extracellular vesicles in blood
期刊论文
Progress in Neurobiology, 2019, 卷号: Vol.175, 页码: 96-106
作者:
Min Shi
;
Lifu Sheng
;
Tessandra Stewart
;
Cyrus P. Zabetian
;
Jing Zhang
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/13
Extracellular
vesicle
Exosome
Brain-periphery
communication
Neurological
disorder
Biomarker
CNS
drug
delivery
Alzheimer
disease
Parkinson
disease
3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.168, 页码: 426-435
作者:
Min'an Zhai
;
Shiyuan Liu
;
Meiqi Gao
;
Long Wang
;
Jun Sun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/13
Ring tethering
Conformational analysis
Pyrazolo[3,4-b]pyridine
Colchicine site
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
期刊论文
Bioorganic & medicinal chemistry letters, 2019
作者:
Kai Cheng
;
Shiyu Li
;
Xiao Lv
;
Yongbin Tian
;
Haiyan Kong
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/12/13
Fragment-based drug design
Isatin
Isoform selectivity
Structure activity relationship
hMAO-B
Pharmacokinetics and Safety evaluation in Healthy Chinese Volunteers of Alkaloids from leaf of Alstonia scholaris, A Multiple Doses Phase I Clinical Trial
期刊论文
Phytomedicine, 2019, 页码: 152828
作者:
Rui Li
;
Ming-Jie Zi
;
Zhong-Ping Gou
;
Yun-Li Zhao
;
Wan-Tong Zhang
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/12/13
capsule
of
alkaloids
from
leaf
of
A.
scholaris
(CALAS)
pharmacokinetics
safety
evaluation
drug
re-excitation
research
Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles
期刊论文
Nano Letters, 2019, 卷号: Vol.19 No.1, 页码: 124-134
作者:
Ruixiang Li
;
Yuwei He
;
Ying Zhu
;
Lixian Jiang
;
Shuya Zhang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
biomimetic
nanoparticles
macrophage-derived
microvesicle
proteomics
Rheumatoid
arthritis
tacrolimus
Identification of factors associated with first-cycle drug approval rates and regulatory outcomes for new drug applications
期刊论文
Pharmacological Research, 2019, 卷号: Vol.139, 页码: 166-172
作者:
Lin-Chau Chang
;
Margaret Vanheusen
;
Xiao Fang
;
Christopher D. Breder
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
First-cycle
approval
Product
attributes
Near-infrared fluorescent carbon dots encapsulated liposomes as multifunctional nano-carrier and tracer of the anticancer agent cinobufagin in vivo and in vitro
期刊论文
Colloids and Surfaces B: Biointerfaces, 2019, 卷号: Vol.174, 页码: 384-392
作者:
Wei Ren
;
Shiqing Chen
;
Yuyang Liao
;
Shumu Li
;
Jiechao Ge
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/13
Carbon
dots
Cinobufagin
Multifunctional
liposomes
Photoluminescence
enhancement
Bio-imaging
Drug
delivery
RBC membrane camouflaged prussian blue nanoparticles for gamabutolin loading and combined chemo/photothermal therapy of breast cancer
期刊论文
Biomaterials, 2019, 页码: 119301
作者:
Bin Liu
;
Wenmiao Wang
;
Jialong Fan
;
Ying Long
;
Feng Xiao
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/13
Photothermal therapy
Chemotherapy
Erythrocyte membrane
Long circulation
Targeted drug delivery
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