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A Learning-Embedded Attributed Petri Net to Optimize Student Learning in a Serious Game
期刊论文
IEEE TRANSACTIONS ON COMPUTATIONAL SOCIAL SYSTEMS, 2021, 页码: 9
作者:
Liang, Jing
;
Tang, Ying
;
Hare, Ryan
;
Wu, Ben
;
Wang, Fei-Yue
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/01/27
Games
Task analysis
Problem-solving
Petri nets
Random forests
Training
Radio frequency
Learning optimization
Petri nets (PNs)
serious game (SG)
An overview of kinase downregulators and recent advances in discovery approaches
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:
Wang, Beilei
;
Wu, Hong
;
Hu, Chen
;
Wang, Haizhen
;
Liu, Jing
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/25
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
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  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
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  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:58/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202]
项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
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  |  
浏览/下载:164/0
  |  
提交时间:2021/05/24
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:
Fan, Xinping
;
Luo, Guanghao
;
Huang, Yu S.
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  |  
浏览/下载:214/0
  |  
提交时间:2021/05/24
Cancer genomics
Copy number alterations
Next-generation sequencing
A Support Vector Machine Based on Liquid Immune Profiling Predicts Major Pathological Response to Chemotherapy Plus Anti-PD-1/PD-L1 as a Neoadjuvant Treatment for Patients With Resectable Non-Small Cell Lung Cancer
期刊论文
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12
作者:
Peng, Jie
;
Zou, Dan
;
Han, Lijie
;
Yin, Zuomin
;
Hu, Xiao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/02/14
non-small cell lung cancer
support vector machine
major pathological response
liquid immune profiling
neoadjuvant treatment
Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020229]
项目
项目编号: XDA12020229, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
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