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科研机构
上海药物研究所 [86]
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期刊论文 [80]
会议论文 [6]
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2021 [3]
2019 [1]
2018 [1]
2017 [9]
2016 [5]
2015 [10]
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Chemistry [4]
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The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:
Wei, Dan
;
Wang, Hanlin
;
Zeng, Qinghe
;
Wang, Wenjing
;
Hao, Bingbing
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/12/16
Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 19
作者:
Wang, Yu-Jun
;
Yu, Chuan
;
Wu, Wei-Wei
;
Ju, Yun-Yue
;
Liu, Yao
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/06/11
Neonatal exposure to ketamine disrupts developmental synapse unsilencing and predisposes adult mice for stressor-evoked anxiety
期刊论文
NEUROPHARMACOLOGY, 2020, 卷号: 180, 页码: 12
作者:
Zhang, Xiaoyun
;
Kong, Yue
;
He, Guiqin
;
Zhou, Zikai
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/05/24
Stress
Anxiety
Silent synapse
Long-term potentiation
Anesthesia
Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal
期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 372, 页码: 8
作者:
Guo, Liu-bin
;
Yu, Chuan
;
Ling, Qing-lan
;
Fu, Yu
;
Wang, Yu-jun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Morphine withdrawal
Aversive memories
Proteomics
Synaptic plasticity
Amygdala
Dorsal hippocampus
Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference
期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2018, 卷号: 353, 页码: 129-136
作者:
Wu, Xue-Qing
;
Zan, Gui-Ying
;
Ju, Yun-Yue
;
Chen, Tian-Zhen
;
Guo, Liu-Bin
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Methamphetamine
rTMS
CPP
Dorsolateral striatum
GABA(B)R1
Dissociative role for dorsal hippocampus in mediating heroin self-administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis
期刊论文
ADDICTION BIOLOGY, 2017, 卷号: 22, 期号: 6, 页码: 1731-1742
作者:
Chen, Zhong-Guo
;
Liu, Xing
;
Wang, Weisheng
;
Geng, Fan
;
Gao, Jing
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
CDK5
dorsal hippocampus
heroin self-administration
label-free proteomic analysis
RhoB
the centrifugal proteomic reactor
Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal
期刊论文
EMBO MOLECULAR MEDICINE, 2017, 卷号: 9, 期号: 11, 页码: 1521-1536
作者:
Zhang, Lei
;
Kibaly, Cherkaouia
;
Wang, Yu-Jun
;
Xu, Chi
;
Song, Kyu Young
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
lentivirus injection
locus coeruleus
naloxone-precipitated opiate withdrawal
opiate addiction
Src-mediated phosphorylation of MOR at Tyr(336)
SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABA(A)alpha 1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10
作者:
Jiao, Dong-Liang
;
Chen, Yan
;
Liu, Yao
;
Ju, Yun-Yue
;
Long, Jian-Dong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
methamphetamine
GABA(A)alpha 1
dorsal striatum
ERAD
SYVN1
The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABA(A) Receptor Endocytosis in the vmPFC
期刊论文
JOURNAL OF NEUROSCIENCE, 2017, 卷号: 37, 期号: 30, 页码: 7096-7110
作者:
Wang, Weisheng
;
Ju, Yun-Yue
;
Zhou, Qi-Xin
;
Tang, Jian-Xin
;
Li, Meng
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
aversive memory
drug withdrawal
endocytosis
extinction
GABA(A) receptor
Rac1
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