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CORC

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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/18
Beshanzoides A-D, unprecedented cycloheptanone-containing polyketides from Penicillium commune P-4-1, an endophytic fungus of the endangered conifer Abies beshanzuensis 期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 63, 页码: 39781-39789
作者:  Chen, Hao-Wei;  Jiang, Chun-Xiao;  Li, Jiyang;  Li, Na;  Zang, Yi
收藏  |  浏览/下载：46/0  |  提交时间：2022/01/18
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Chen, Cheng;  Ren, Yong-mei;  Zhu, Jian-zhong;  Chen, Jia-li;  Feng, Zhe-ling
收藏  |  浏览/下载：56/0  |  提交时间：2022/01/04
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04
Two New Oleanane-Triterpenoid Saponins from Clinopodium gracile 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 页码: 8
作者:  Zhao, Ting;  Liu, Yi-Nan;  Sun, Xin-Yu;  Li, Jing-Ya;  Lei, Chun
收藏  |  浏览/下载：15/0  |  提交时间：2021/12/01
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains 期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 10, 页码: 2218-+
作者:  Song, Bin;  Chen, Yun;  Liu, Xin;  Yuan, Fei;  Tan, Eddie Yong Jun
收藏  |  浏览/下载：23/0  |  提交时间：2021/12/01
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing
收藏  |  浏览/下载：19/0  |  提交时间：2021/12/01
Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:  Xiong, Juan;  Zhou, Peng-Jun;  Jiang, Hao-Wen;  Huang, Ting;  He, Yu-Hang
收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:  Wu, Xu;  Yin, Chun;  Ma, Jiang;  Chai, Stella;  Zhang, Chunyuan
收藏  |  浏览/下载：36/0  |  提交时间：2021/11/04
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:  Huang, Suling;  Wu, Yanwei;  Zhao, Zhuohui;  Wu, Bing;  Sun, Kai
收藏  |  浏览/下载：88/0  |  提交时间：2021/08/17

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