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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Shank3 mutations enhance early neural responses to deviant tones in dogs
期刊论文
CEREBRAL CORTEX, 2023, 页码: 12
作者:
Wu, Liang
;
Mei, Shuting
;
Yu, Shan
;
Han, Shihui
;
Zhang, Yong Q.
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  |  
浏览/下载:3/0
  |  
提交时间:2023/11/17
auditory processing
autism
dog
electrocorticogram
Shank3
SETD2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage
期刊论文
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2022, 卷号: 113
作者:
Fan, Xiaoqing
;
Sun, Suling
;
Yang, Haoran
;
Ma, Huihui
;
Zhao, Chenggang
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  |  
浏览/下载:17/0
  |  
提交时间:2022/12/23
Genomic variation associated with carcinoma showing thymus-like elements (CASTLE) in thyroid gland
期刊论文
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY, 2022
作者:
Jiang, Lin
;
Zheng, Wei-Hui
;
Chen, Chao
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  |  
浏览/下载:8/0
  |  
提交时间:2022/12/23
CASTLE
genomic variation
immunohistochemistry
prognosis
thyroid
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
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  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
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  |  
浏览/下载:76/0
  |  
提交时间:2022/02/14
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
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  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
Seq-SetNet: directly exploiting multiple sequence alignment for protein secondary structure prediction
期刊论文
BIOINFORMATICS, 2022, 卷号: 38, 期号: 4, 页码: 990-996
作者:
Ju, Fusong
;
Zhu, Jianwei
;
Zhang, Qi
;
Wei, Guozheng
;
Sun, Shiwei
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  |  
浏览/下载:12/0
  |  
提交时间:2023/01/16
RECOGNITION
FRAGMENTS
FOLD
OsMADS14 and NF-YB1 cooperate in the direct activation of OsAGPL2 and Waxy during starch synthesis in rice endosperm
期刊论文
NEW PHYTOLOGIST, 2022, 卷号: 234, 期号: 1, 页码: 77-92
作者:
Feng, Tingting
;
Wang, Lili
;
Li, Laiyun
;
Liu, Yuan
;
Chong, Kang
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  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
endosperm
MADS-box gene
NF-YB1
Oryza sativa
OsMADS14
protein-protein interaction
starch synthesis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
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