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上海药物研究所 [40]
山东大学 [18]
厦门大学 [13]
中南大学 [11]
海洋研究所 [10]
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期刊论文 [233]
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Potential roles of MEK1 on aging in Argopecten scallops
期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 16
作者:
Yuan, Ke
;
Lu, Xia
;
Ning, Junhao
;
Chen, Min
;
Wang, Quanchao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/08/17
bivalve
Argopecten scallops
MEK1
aging
nutrition restriction
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity
期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13
作者:
Wang, Ruru
;
Shang, Yajing
;
Chen, Bin
;
Xu, Feng
;
Zhang, Jie
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Cold Atmospheric Plasma Inhibits the Proliferation of CAL-62 Cells through the ROS-Mediated PI3K/Akt/mTOR Signaling Pathway
期刊论文
SCIENCE AND TECHNOLOGY OF NUCLEAR INSTALLATIONS, 2022, 卷号: 2022
作者:
Liu, Fang
;
Zhou, Yuanyuan
;
Song, Wencheng
;
Wang, Hongzhi
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/22
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches
期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:
Wang, Xiaoqing
;
Wang, Li
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/06/16
Toxicity pathways
Lipid metabolism disorder
Bibliometric analysis
Computational toxicology
Data-driven analysis
Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 期号: 5, 页码: 1-15
作者:
Liu, XY (Liu, Xiao Yan) [1] , [2] , [3]
;
Peng, J (Peng, Jun) [1] , [2]
;
He, F (He, Fei) [1]
;
Tursun, X (Tursun, Xirali) [4]
;
Li, SP (Li, Shu Ping) [1]
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2022/06/06
shabyar
retinal pigment epithelium
autophagy
aldose reductase
traditional medicine formula
Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis
期刊论文
BIOENGINEERED, 2021, 卷号: 12
作者:
Zhang, Runze
;
Lian, Yanhong
;
Xie, Kangjie
;
Cai, Yunfang
;
Pan, Yafei
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
Ropivacaine
hepatocellular carcinoma
IGF-1R
IGF1R-PI3K-AKT-mTOR signaling
cell cycle
epithelial-mesenchymal transition
Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:
Hu, Lin
;
Chen, Fuxian
;
Wu, Chao
;
Wang, Jun
;
Chen, Si-si
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/18
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:
Zhang, Jiajia
;
Wu, Ning
;
Shi, Dayong
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/05/11
Signaling pathway
mammalian target of rapamycin
protein tyrosine phosphatase 1b
dipeptidase 4
cancer
diabetes
pharmacology
target compounds
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